Authors
Aslanov A.D.1, 2, Kalibatov R.M.1, 3, Logvina O.E.1, Kardanova L.Yu.1, 2, Baksanokov Z.H.5, Bakov Z.N.4
1 Kabardino-Balkarian State University named after H.M. Berbekov, Nal’chik
2 Republican Clinical Medical and Surgical Center of the Ministry of Health of the KBR, Nal’chik
3 Ministry of Health of the Kabardino-Balkarian Republic, Nal’chik
4 Republican Clinical Multidisciplinary Center of High Medical Technologies of the Ministry of Health of the KBR, Nal’chik
5 Central district Hospital of the Tersk district, Terek
Abstract
Backgraund: One of the common complications of GI is mechanical jaundice. This complication is accompanied by a high mortality rate.
Aims: to reduce the risk of complications of cholelithiasis by restoring the outflow of bile from the liver as soon as possible and selecting antibacterial therapy.
Materials and methods: 366 patients without cholangitis clinic and without increased amylase levels were analyzed. The patients were divided into 3 groups: the first – patients with prolonged use of antibacterial therapy, the second – patients with short–term use of antibacterial therapy, the third - patients who underwent endoscopic manipulations.
Results: the results of the comparative analysis indicated that only the combined use of each of the groups leads to a favorable outcome in patients with cholelithiasis.
Conclusions: the study confirms that combined treatment, taking into account bacteriological analysis and the special clinical circumstances of patients, can significantly improve outcomes and reduce mortality. Future research should focus on optimizing antibiotic therapy regimens to improve their effectiveness and safety.
Keywords: gallstone disease, mechanical jaundice, antibacterial therapy, resistance.
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