DOI: 10.25881/20728255_2022_17_4_S1_6

Authors

Kulikov A.N., Skvortsov V.Yu., Tulin D.V.

S.M. Kirov Military Medical Academy

Abstract

The choice of the method of surgical treatment of glaucoma, as a way to control intraocular pressure and to stabilize the glaucoma, is one of the leading problems in ophthalmology. Abilities to control power and time of laser cyclodestructive exposure makes it possible to expand the range of tasks that the method can solve. The aim of the study was a comparative assessment of the degree of postoperative inflammatory response in the anterior chamber of the eye to cyclodestructive intervention, accompanied by the implementation of the vaporization biological effect and without it.

In first experimental group of the eyes of rabbits, the intervention was performed until a visual response was obtained in the form of coagulation of processes with a power in the range from 0.3 to 0.5 W. In second group intervention was performed until a visual response was obtained in POP-effect. There were the power range from 0.9 to 1.2 W.

We hadn’t statistically significant differences between groups throughout the observation period. Endoscopic laser cyclodestruction leads to an inflammatory response, however, even somewhat excessive damage to the ciliary processes in the form of a vaporization effect does not lead to a significant increase in its intensity.

Keywords: postoperative iridocyclitis; endoscopic laser cyclodestruction; optical coherence tomography.

References

1. Vogt A. et al. Versuche zur intraokularen druckherabsetzung mittelst diathermieschädigung des corpus ciliare (Zyklodiathermiestichelung). Klin Monatsbl Augenheilkd. 1936; 97: 672-673.

2. Haik G.M., Breffeilh L. A., Barber F. Beta irradiation as a possible therapeutic agent in glaucoma; an experimental study with the report of a clinical case. Am. J. Ophthalmol. 1948. Vol. 31. P. 945–952. https://doi.org/10.1016/0002-9394(48)92523-9.

3. Bietti G. Surgical interventions on the ciliary body; new trends for the relief of glaucoma // J Am Med Assoc. 1950. Vol. 142. P. 889-896. https://doi.org/10.1001/jama.1950.02910300027006.

4. Purnell E.W., Sokollu A., Torchia R., Taner N. Focal chorioretinitis produced by ultrasound. Invest Ophthalmol. 1964. Vol. 3. P. 657–664.

5. Uram M. Ophthalmic laser microendoscope ciliary process ablation in the management of neovascular glaucoma. Ophthalmology. 1992. Vol. 99. P. 1823–1828. https://doi.org/10.1016/s0161-6420(92)31718-x.

6. Chen J, Cohn R.A., Lin S.C., Cortes A.E., Alvarado J.A. Endoscopic photocoagulation of the ciliary body for treatment of refractory glaucomas. Am J Ophthalmol. 1997. Vol. 124, N. 6. P. 787-796. https://doi.org/10.1016/s0002-9394(14)71696-4.

7. Uram M. Combined phacoemulsification, endoscopic ciliary process photocoagulation, and intraocular lens insertion in glaucoma management. Ophthalmic Surg. 1995. Vol. 26, N 4. P. 346-352.

8. Francis B.A., Berke S.J., Dustin L., Noecker R. Endoscopic cyclophotocoagulation combined with phacoemulsification versus phacoemulsification alone in medically controlled glaucoma. J Cataract Refract Surg. 2014. Vol. 40. P. 1313–1321. https://doi.org/10.1016/j.jcrs.2014.06.021.

9. Siegel M.J., Boling W.S., Faridi O.S., et al. Combined endoscopic cyclo-photocoagulation and phacoemulsification versus phacoemulsification alone in the treatment of mild to moderate glaucoma. Clin Experiment Ophthalmol. 2015. Vol. 43. P. 531–539. https://doi.org/10.1111/ceo.12510.

10. Volkov V.V., Kachanov A.B. Diode laser transscleral contact cyclocoagulation in the treatment of secondary glaucoma and ophthalmohypertensions. Ovtal’mologitscheckiy zhurnal. 1993. Vol. 3. P. 274–277 (In Russ.).

11. Gaasterland, D.E., Pollack I.P. Initial experience with a new method of laser transscleral cyclophotocoagulation for ciliary ablation in severe glaucoma. Trans Am Ophthalmol Soc. 1992. Vol. 90. P. 225–246.

12. Boiko E.V., Kulikov A.N., Skvortsov V.U. Comparative evaluation of diode laser thermotherapy and laser coagulation as methods of cyclodestruction (experimental study). Practical medicine. Ophthalmology. 2012. Vol. 1. P. 175-179. (in Russ.)

13. Tulin D.V., Kulikov A.N., Skvorcov V.Ju. Sravnitel’nyj analiz nekotoryh parametrov bezopasnosti primenenija jendoskopicheskoj lazernoj ciklodestrukcii i transskleral’noj lazernoj ciklotermoterapii pri hirurgicheskom lechenii glaukomy // Sovremennye tehnologii v oftal’mologii. 2018. T. 1, № 4. S. 247-249. (In Russ.).

For citation

Kulikov A.N., Skvortsov V.Yu., Tulin D.V. Influence of modes of the endoscopic laser cyclodestruction on the inflammatory response in the anterior chamber of the eye (experimental study). Bulletin of Pirogov National Medical & Surgical Center. 2022;17(4,supplement):6-7. (In Russ.) https://doi.org/10.25881/20728255_2022_17_4_S1_6