DOI: 10.25881/20728255_2022_17_3_94

Authors

Shevchenko Yu.L., Ermakov D.Yu., Marchak D.I.

St. George thoracic and cardiovascular surgery clinic Pirogov National Medical and Surgical Center, Moscow

Abstract

The article discusses the pathogenesis of coronary bypass graft (CABG) failure, as well as thrombosis and restenosis of coronary stents (CS). The data of clinical studies on dysfunction of coronary venous and autoarterial conduits and failure of target lesions of stented areas of coronary arteries in patients with CAD were systematically analyzed. The main directions of further promising directions for scientific research in the field of approaches to repeated invasive correction of the pathology of the coronary bed are determined.

Keywords: coronary artery disease, coronary intervention, coronary artery bypass grafting, restenosis, thrombosis, bypass dysfunction, repeated coronary operations.

References

1. Kayumova MM, Gakova EI, Senatorova OV. Epidemiologicheskie aspekty rasprostranennosti ishemicheskoj bolezni serdca v otkrytoj gorodskoj populyacii: gendernye razlichiya. Sibirskij medicinskij zhurnal. 2019; 34(2): 146–151. (In Russ). doi: 10.29001/2073-8552-2019-34-2-146-151.

2. Vsemirnaya organizaciya zdravoohraneniya. Evropejskoe regional’noe byuro. [URL] (In Russ).

3. Bojcov SA, Demkina AE, Oshchepkova EV, Dolgusheva YU A. Dostizheniya i problemy prakticheskoj kardiologii v Rossii na sovremennom etape. Kardiologiya. 2019; 59(3): 53–59. (In Russ). doi: 10.18087/cardio.2019.3.10242.

4. Bojcov SA, Andreev EM, Samorodskaya IV. Ocenka vozmozhnosti sravneniya pokazatelej smertnosti ot boleznej sistemy krovoobrashcheniya v Rossii i SSHA. Kardiologiya. 2017; 1: 5–16. (In Russ). doi: 10.18565/cardio.2017.1.5–16.

5. Neumann FJ, Sousa-Uva M, Ahlsson A, Alfonso F, Banning AP, Benedetto U, Byrne RA, Collet JP, Falk V, Head SJ, Jüni P, Kastrati A, Koller A, Kristensen SD, Niebauer J, Richter DJ, Seferovic PM, Sibbing D, Stefanini GG, Windecker S, Yadav R, Zembala MO. ESC Scientific Document Group. 2018 ESC/EACTS Guidelines on myocardial revascularization. European Heart Journal. 2019; 40(2): 87–165. doi: 10.1093/eurheartj/ehy394.

6. Goluhova EZ, Semenov VYU, Kovalenko OA. Razvitie medicinskoj pomoshchi po profilyu «serdechno-sosudistaya hirurgiya» v Central’nom, Privolzhskom i Severo-Kavkazskom federal’nyh okrugah v ramkah realizacii regional’nyh programm «Bor’ba s serdechno-sosudistymi zabolevaniyami». Byulleten’ NCSSKH. 2021; 22(2): 195-204. (In Russ).

7. SHevchenko YUL, Simonenko VB, Borshchev GG, Ul’bashev DS, Zemlyanov AV. Rol’ vospaleniya v geneze ateroskleroza. Klinicheskaya medicina. 2019; 97(1): 5-13. (In Russ).

8. SHevchenko YUL, Borshchev GG, Ul’bashev DS, Zemlyanov AV. Vybor konduitov v koronarnoj hirurgii. Vestnik Nacional’nogo mediko-hirurgicheskogo Centra im. N. I. Pirogova. 2019; 14(1): 97-104. (In Russ).

9. Kochergin NA, Frolov AV, Ganyukov VI. Disfunkciya koronarnyh shuntov. Ateroskleroz i dislipidemii. 2018; 4: 25-35. (In Russ).

10. SHevchenko UL, Borshchev GG. Ekstrakardial’naya revaskulyarizaciya miokarda u bol’nyh IBS s diffuznym porazheniem koronarnogo rusla. M: NMHC im. N.I. Pirogova, 2022. 292 s. (In Russ).

11. CHaulin AM, Grigor’eva AV, Duplyakov DV. Sovremennye predstavleniya o patofiziologii ateroskleroza. CHast’ 1. Rol’ narusheniya obmena lipidov i endotelial’noj disfunkcii. Medicina v Kuzbasse. 2020; 2: 34-41. (In Russ).

12. Shiono Y, Kubo T, et al. Impact of functional focal versus diffuse coronary artery disease on bypass graft patency. Int J Cardiol. 2016; 222: 16-21. doi: 10.1016/j.ijcard.2016.07.052.

13. Meirson T, Orion E, Di Mario C, Webb C, Patel N, Channon KM, Ben Gal Y, Taggart DP. Flow patterns in externally stented saphenous vein grafts and development of intimal hyperplasia. J Thorac Cardiovasc Surg. 2015; 150: 871–878. doi: 10.1016/j.jtcvs.2015.04.061.

14. Williams JB, Peterson ED, et al. Association between endoscopic vs open vein-graft harvesting and mortality, wound complications, and cardiovascular events in patients undergoing CABG surgery. JAMA. 2012; 308: 475-84. doi: 10.1001/jama.2012.8363.27.

15. Cao C, Manganas C, Horton M, Bannon P, Munkholm-Larsen S, Ang SC, Yan TD. Angiographic outcomes of radial artery versus saphenous vein in coronary artery bypass graft surgery: a meta-analysis of randomized controlled trials. J Thorac Cardiovasc Surg. 2013; 146: 255-61. doi: 10. 1016/j.jtcvs.2012.07.014.

16. Goldman S, Zadina K, Moritz T, Ovitt T, Sethi G, Copeland JG, Thottapurathu L, Krasnicka B, Ellis N, Anderson RJ, Henderson W. VA Cooperative Study Group #207/297/364. Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative Study. J Am Coll Cardiol. 2004; 44: 2149-2156. doi: 10.1016/j.jacc.2004.08.064.

17. Tatoulis J, Buxton BF, Fuller JA. Patencies of 2127 arterial to coronary conduits over 15 years. Ann Thorac Surg. 2004; 77: 93–101.

18. Tatoulis J, Buxton BF, Fuller JA. The right internal thoracic artery: the forgotten conduit–5,766 patients and 991 angiograms. Ann Thorac Surg. 2011; 92: 9–15. doi: 10.1016/j.athoracsur.2011.03.099.

19. Deb S, Cohen EA, Singh SK, Une D, Laupacis A, Fremes SE. RAPS Investigators. Radial artery and saphenous vein patency more than 5 years after coronary artery bypass surgery: results from RAPS (Radial Artery Patency Study). J Am Coll Cardiol. 2012; 60: 28–35. doi: 10.1016/j.jacc.2012.03.037.6.

20. Hess CN, Lopes RD, et al. Saphenous vein graft failure after coronary artery bypass surgery: insights from PREVENT IV. Circulation. 2014; 130: 1445–51. doi: 10.1161/CIRCULATIONAHA.113.008193.7.

21. Cao C, Manganas C, Horton M, Bannon P, Munkholm-Larsen S, Ang SC, Yan TD. Angiographic outcomes of radial artery versus saphenous vein in coronary artery bypass graft surgery: a meta-analysis of randomized controlled trials. J Thorac Cardiovasc Surg. 2013; 146: 255–61. doi: 10.1016/j.jtcvs.2012.07.014.8.

22. Collins P, Webb CM, Chong CF, Moat NE. Radial Artery Versus Saphenous Vein Patency (RSVP) Trial Investigators. Radial artery versus saphenous vein patency randomized trial: five-year angiographic follow-up. Circulation. 2008; 117: 2859–64. doi: 10.1161/CIRCULATIONAHA.107.736215.9.

23. Achouh P, Acar C. Twenty-year fate of the radial artery graft. Ann Cardiothorac Surg. 2013; 2: 481–484. doi: 10.3978/j.issn.2225–319X.2013.07.13.

24. Buxton BF, Hayward PA, Matalanis G, Monten S, Horrigan M, Rosalion A. 10-year endpoint of RAPCO is reached: clinical and angiographic results of a randomised trial of radial artery versus right internal thoracic artery or saphenous vein for the second graft. Presented at the 96th annual meeting of the American Association for Thoracic Surgery. May 14–18, 2016, Baltimore, MD.

25. Viller AG, Harpunov VF, Bolomatov NV, Marchak DI, D’yachkov SI, Matusov AV. Otdalennye rezul’taty endovaskulyarnoj hirurgii vnutristentovogo restenoza venechnyh arterij. Vestnik Nacional’nogo mediko-hirurgicheskogo Centra im. N. I. Pirogova. 2013; 8(2): 15-23. (In Russ).

26. Marchak DI. Endovaskulyarnoe primenenie antiproliferativnogo preparata v lechenii pacientov s vnutristentovym restenozom venechnyh arterij. [dissertation] Moskva; 2013. (In Russ).

27. Berezovskaya GA, Ganyukov VI, Karpenko MA. Restenoz i tromboz vnutri stenta: patogeneticheskie mekhanizmy razvitiya i prognosticheskie markery. Rossijskij kardiologicheskij zhurnal. 2012; 6: 91-95. (In Russ).

28. Alimov DA, ZHalalov BZ, Ganiev USH. Restenoz stenta s tochki zreniya endotelial’noj disfunkcii. Vestnik ekstrennoj mediciny. 2017; 3: 109-112. (In Russ).

29. Tajmanuly O, Sagatov IE, Uteuliev ES, Myrzagulova AO, Maslov TV. Tromboz stentov u pacientov s ishemicheskoj bolezn’yu serdca: klassifikaciya, prichiny i metody lecheniya. Sistematicheskij obzor. Vestnik KazNMU. 2017; 4: 52-56. (In Russ).

30. Dygaj AM. K voprosu ob antiproliferativnom pokrytii koronarnyh stentov. Patologiya krovoobrashcheniya i kardiohirurgiya. 2018; 22(2): 22-29. (In Russ).

31. Bangalore S, Toklu B, et al. Bare metal stents, durable polymer drug eluting stents, and biodegradable polymer drug eluting stents for coronary artery disease: mixed treatment comparison meta-analysis. BMJ. 2013; 347: f6625. doi: 10.1136/bmj.f6625.

32. Byrne RA, Serruys PW, et al. Report of a European Society of Cardiolog — European Association of Percutaneous Cardiovascular Interventions task force on the evaluation of coronary stents in Europe: executive summary. European Heart Journal. 2015; 36: 2608-20. doi: 10.1093/eurheartj/ehv203.

33. Prohorihin AA, Bajstrukov VI, Grazhdankin IO, Ponomarev DN, Verin VV, Osiev AG, Ganyukov VI, Protopopov AV, Demin VV, Abugov SA, Bojkov AA, Malaev DU, Karas’kov AM, Pokushalov EA, Kretov EI. Prostoe slepoe prospektivnoe randomizirovannoe mul’ticentrovoe issledovanie effektivnosti i bezopasnosti sirolimus-dostavlyayushchego koronarnogo stenta «KalIpsO» i everolimus-dostavlyayushchego koronarnogo stenta XiencePrime: rezul’taty issledovaniya «PATRIOT». Patologiya krovoobrashcheniya i kardiohirurgiya. 2017; 21(3): 76-85. (In Russ). doi: 10.21688/1681-3472-2017-3-76-85.

34. Kok M.M., Zocca P., et al. Two-year clinical outcome of all-comers treated with three highly dissimilar contemporary coronary drug-eluting stents in the randomised BIO-RESORT trial. EuroIntervention. 2018; 14(8): 915-923. doi: 10.4244/EIJ-D-18-00336.

35. Pilgrim T, Piccolo R, et al. Ultrathin-strut, biodegradable-polymer, sirolimus-eluting stents versus thin-strut, durable-polymer, everolimus-eluting stents for percutaneous coronary revascularisation: 5-year outcomes of the BIOSCIENCE randomised trial. Lancet. 2018; 392(10149): 737-746. doi: 10.1016/S0140-6736(18)31715-X.

36 Palmerini T, Dangas G, Mehran R, et al. Predictors and implications of stent thrombosis in non-ST-segment elevation acute coronary syndromes: the ACUITY Trial. Circ Cardiovasc Interv. 2011; 4(6): 577-584. doi: 10.1161/ CIRCINTERVENTIONS.111.963884.

37. Dangas GD, Claessen BE, Mehran R, et al. Clinical outcomes following stent thrombosis occurring in-hospital versus out-of-hospital: results from the HORIZONS-AMI (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction) trial. J Am Coll Cardiol. 2012; 59(20): 1752–1759. doi: 10.1016/j.jacc.2011.12.042.

38. Wiviott SD, Braunwald E, McCabe CH, et al. Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomised trial. Lancet. 2008; 371(9621): 1353–1363. doi: 10.1016/ S0140-6736 (08) 60422-5.

39. SHumakov DV, SHekhyan GG, Zybin DI, et al. Pozdnie oslozhneniya chreskozhnyh koronarnyh vmeshatel’stv. RMZH. 2020; 10: 25-28. (In Russ).

40. Grebennik VK, Kucherenko VS, Fan’ H, Gordeev ML. Povtornoe aorto-koronarnoe shuntirovanie. Riski i rezul’taty. Vestnik Nacional’nogo mediko-hirurgicheskogo Centra im. N.I. Pirogova. 2018; 13(3): 20-24. (In Russ).

41. SHevchenko YUL, Ul’bashev DS, Borshchev GG, Vahromeeva MN, Vahrameeva AYU. Sravnitel’naya ocenka dannyh scintigrafii v blizhajshie i otdalennye periody posle razlichnyh metodov korrekcii koronarnogo krovoobrashcheniya u bol’nyh IBS. Vestnik Nacional’nogo mediko-hirurgicheskogo Centra im. N.I. Pirogova. 2020; 15(2): 16-25. (In Russ).

42. SHevchenko YUL, Ermakov DYU. Elektrokardiografiya iz venechnogo sinusa. M.: Izdatel’stvo «NMHC im. N.I. Pirogova». 2022. 136 s. (In Russ).

For citation

Shevchenko Yu.L., Ermakov D.Yu., Marchak D.I. Dysfunction of coronary bypass grafts and stents after surgical myocardial revascularization in patients with coronary artery disease: pathogenesis, risk factors and clinical assessment. Bulletin of Pirogov National Medical & Surgical Center. 2022;17(3):94-100. (In Russ.) https://doi.org/10.25881/20728255_2022_17_3_94