DOI: 10.25881/20728255_2021_16_3_121

Authors

Davydov D.V.1, Al’-Hanih M.A.1, Brizhan’ L.K.1, Gricyuk A.A.2

1 Chief military clinical hospital named after academic N.N. Burdenko, Moscow

2 I.M. Sechenov First Moscow State Medical University, Moscow

Abstract

The article describes a clinical case of treatment of an atrophic pseudarthrosis of the clavicle, which arose after the primary surgical treatment — osteosynthesis with a plate with insufficient rigidity. After removal of the hardware, the pseudarthrosis progressed. Adequate fixation and bone grafting were performed, however, early removal of the plate without considering local factors of adhesion led to the recurrence of the pseudarthrosis, with a sharp decrease in the regenerative capacity of the clavicle. This clinical situation was successfully resolved by repeated plate osteosynthesis and bone grafting using scaffold technology. Biopolymer microheterogeneous collagen-containing gel (BMCG) made it possible to restore the regenerative properties of bone tissue and achieve fusion of the atrophic pseudarthrosis of the clavicle, and adequately restore the function of the upper limb. The analysis of the clinical case showed the importance of correct assessment of the clinical manifestations of impaired bone regenerative functions and made it possible to illustrate the possibilities of tissue engineering technologies in orthopedic surgical practice.

Keywords: сase report Scaffold technologies, atrophic pseudarthrosis, pseudarthrosis of the clavicle.

References

1. Ilizarov GA, Shevtsov VI. Bloodless compression-distraction osteosynthesis in the treatment of pseudoarthrosis of the humerus. Military Medical Journal. 1974; 295(6): 27-31. (In Russ).

2. Tkachenko SS, Gaidukov VM. Compression osteosynthesis in the treatment of false joints of the forearm bones. Orthopedics, traumatology and prosthetics. 1991; 2: 16-20. (In Russ).

3. Azizov MJ, Abdulhakov NT, Raximov AM. Surgical treatment of pseudoarthrosisis of the forearms bones. Postgraduate doctor. 2013; 57(2.2): 245-249. (In Russ).

4. Perova NV, Sevastyanov VI. Biopolymer heterogeneous hydrogel Sphero®GEL — injection biodegradable implant. Practical Medicine. 2014; 8(84): 111-116. (In Russ).

5. Sevаstyanov VI. Cellular engineering structures in tissue engineering and reparative medicine. Bulletin of transplantology and artificial organs. 2015; 17(2): 127-130. (In Russ).

6. Davydov DV, Chirva YuV, Brizhan LK, et al. A promising method of bone tissue restoration in patients with severe osteoregeneration disorders (experience of clinical application of scaffold technologies). Polytrauma. 2021; 1: 41-50. (In Russ). doi: 10.24411/1819-1495-2020-10005.

For citation

Davydov D.V., Al’-Hanih M.A., Brizhan’ L.K., Gricyuk A.A. Scaffold technologies in the treatment of atrophic pseudarthrosis of the clavicle. Bulletin of Pirogov National Medical & Surgical Center. 2021;3(16):121-124. (In Russ.) https://doi.org/10.25881/20728255_2021_16_3_121