Authors
Rustamova Ya.K.1, Imanov G.G.2, Azizov V.A.1, Maksimkin D.A. 3, Faybushevich A.G.3
1 Azerbaijan Medical University, Department of Internal Diseases № 2, Baku, Azеrbaycan Respublikas
2 Azerbaijan Medical University, Department of Internal Diseases № 1 Baku, Azеrbaycan Respublikas
3 Peoples Friendship University of Russia (RUDN University), Moscow
Abstract
The study presented the effectiveness of percutaneous coronary interventions (PCI) in post-MI patients with multivessel coronary disease complicated concomitant diabetes mellitus and heart failure. After 18 months of follow-up, there were no significant differences between the groups of patients with and without diabetes (10,4 and 8,1%, respectively; p = 0,264) in terms of the incidence of major adverse cardiovascular events. In the group of patients with diabetes, as well as in patients without diabetes, there is a significant improvement in the rate of global contractility of the left ventricular myocardium. However, recovery of the function of hibernated myocardium after PCI, is significantly slower compared with patients without diabetes. In patients with diabetes, the number of identified pathological segments in the zone of hibernated myocardium directly correlates with the index of transmurality. The smaller the transmurality index, the smaller the number of pathological segments, and the better the recovery process of dysfunctional myocardium. The index of cardiac fibrosis does not correlate with the number of pathological segments in the hibernation zone. However, a significant change in myocardial function recovery was observed after the intervention was performed with different volumes of cardiac fibrosis, with the exception of patients with a fibrosis volume of 50% or more.
Keywords: diabetes mellitus type 2, dysfunctional myocardium, cardiac magnetic resonance.
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