DOI: 10.25881/BPNMSC.2020.39.95.004

Authors

Kiryaev A.A.1, Travin N.O.2, Semitko S.P.1, Ioseliani D.G.1, Pankov A.N.1, Chernysheva I.E.1

1 Scientific and practical center of interventional cardiology of the first Moscow state medical University I. M. Sechenov, Moscow

2 Central military clinical hospital. P.V. Mandryka, Moscow

Abstract

The article describes a new indicator — the volume/time ratio (VTR), which reflects the adequacy of cardioplegia during cardiac surgery. The method for its calculation is given. The possibility of calculating the required volume of a cardioplegic solution depending on the expected duration of aortic clamping with the help of a VTR has been demonstrated. The effectiveness and reliability of cardioplegia performed by infusion of reduced Custodiol volumes (1000–1500 ml) was shown. Prospects for optimizing myocardial protection based on a smoother Custodiol distribution with its fractional infusion during aortic clamping, have been outlined.

Keywords: Custodiol®, the effectiveness of myocardial protection, volume/time ratio, low-dose cardioplegia, single-shot cardioplegia, multi-dose cardioplegia.

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For citation

Kiryaev A.A., Travin N.O., Semitko S.P., Ioseliani D.G., Pankov A.N., Chernysheva I.E. Calculating the volume/time ratio – a way to optimize cardioplegia custodiol. Bulletin of Pirogov National Medical & Surgical Center. 2019;14(4):22-26. (In Russ.) https://doi.org/10.25881/BPNMSC.2020.39.95.004