DOI: 10.25881/BPNMSC.2019.30.35.004


Bocharov A.V.1, Popov L.V.2

1 Kostroma Regional Clinical Hospital named after Korolev E.I., Kostroma

2 Pirogov National Medical and Surgical Center, Clinic of Thoracic and Cardiovascular Surgery St. George’s, Moscow


Aim. Comparison of long-term results of stenting of extended stenoses (lesion length ≥55 mm) of clinically-dependent arteries in acute coronary syndrome without ST segment elevation in groups with implantation of super long stents with a drug coating or with a combination of a stent with a bare-metal stent.

Materials and methods. The sample consisted of 61 patients with coronary artery disease and multivessel coronary artery lesions who underwent emergency stenting of extensive stenosis of the clinically-dependent artery for acute coronary syndrome without ST segment elevation, and later — complete functional revascularization no later than 90 days from the date of the first stage. Complete functional revascularization was performed using the endovascular method using 3 generation stents with a drug coating and the biodegradable polymer “Calipso”. The minimum total length of the area to be stent was 55 mm. The main group consisted of 31 patients who underwent clinical-dependent artery revascularization using the endovascular method using 1 3rd generation super long stent with drug-coated sirolimus and biodegradable polymer “Biomime”. 30 patients, the control group, revascularization of the clinical-dependent artery was also performed with a combination of overlapped implanted stents, one of which was the 3rd generation medicinal sirolimus stent and the biodegradable polymer “Calipso”, and the bare metal stent “Sinus” another.

Results.There were no statistically significant differences between the groups in clinical, demographic and operational characteristics. Analysis of the results revealed a significant difference between the groups in terms of the frequency of repeated revascularization of the target artery and the frequency of MACCE events that were observed more often in the control group.

Conclusions. When performing extended stenting of a clinic-dependent artery in patients with acute coronary syndrome without ST-segment elevation, the use of extra-long 3-generation stents with a drug coating is effective and safe. Overlapping of the drug-eluting stent and the bare-metal stent should be avoided, as this is associated with a large number of repeated revascularization of the target vessel and large cardiovascular events. This strategy can be recommended for use in case of need to completely cover the stenotic lesion or close the dissection in the absence of drug-eluting stents.

Keywords: acute coronary syndrome without ST segment elevation, coronary heart disease, drug-eluting stent, bare-metal stent, extended stenting.


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For citation

Bocharov A.V., Popov L.V. Compare long-term results of stenting coronary artery stenosis extended with the use of very length of the stent or a combination of drug-eluting stents and bare metal stents in patients with acute coronary syndrome without ST-segment elevation and multivessel disease. Bulletin of Pirogov National Medical & Surgical Center. 2019;14(3):28-31. (In Russ.)