DOI: 10.25881/20728255_2026_21_1_170

Authors

Zarubin M.V.1, 2, Zaznobov M.E.1, Kuvshinova V.A.1, Ihiseeva L.V.1, Agapitov E.A.1, Yankova T.S.1, Senderova O.M.3, Zhiburt E.B.4

1 Irkutsk Regional Blood Transfusion Station, Irkutsk

2 Irkutsk State Medical University, Irkutsk

3 Irkutsk Regional Clinical Hospita, Irkutsk

4 Pirogov National Medical Surgical Center, Moscow

Abstract

The first clinical observation in domestic donor practice of the development of erythrocyte hemolysis during hardware plasmapheresis in a donor with a decrease of the activity of glucose-6-phosphate dehydrogenase in erythrocytes is presented.

Keywords: hemolysis, donor, plasmapheresis, enzymopathy, glucose-6-phosphate dehydrogenase.

References

1. Heller P, Best WR, Nelson RB, Becktel J. Clinical implications of sickle-cell trait and glucose-6-phosphate dehydrogenase deficiency in hospitalized black male patients. N Engl J Med. 1979; 300(18): 1001-1005. doi: 10.1056/ NEJM197905033001801.

2. Luzzatto L, Nannelli C, Notaro R. Glucose-6-phosphate dehydrogenase deficiency. Hematol Oncol Clin North Am. 2016; 30(2): 373-93. doi: 10.1016/j.hoc.2015.11.006.

3. Belov AI, Evdokimova MV, Motina AN. et al. Hereditary hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency in erythrocytes. Modern problems of science and education. 2020; 2: 173. (In Russ.) doi: 10.17513/spno.29550.

4. Pfeffer DA, Ley B, Howes RE et al. Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis. PLoS Med. 2020; 14; 17(5): e1003084. doi: 10.1371/journal.pmed.1003084.

5. Kulagyn AD, Moiseev IS, Smirnova AG. Hemolytic anemias. Educational and methodological manual. St. Petersburg. 2020. (In Russ.)

6. Shevchenko YL, Karpov OE, Zhiburt EB. Blood transfusion: history and modernity (on the 100th anniversary of blood transfusion in Russia). Vestnik Nacional’nogo mediko-hirurgicheskogo centra im. N.I. Pirogova. 2019; 14(4): 4-11. (In Russ.) doi: 10.25881/ BPNMSC.2020.29.78.001.

7. Zhiburt EB, Madzaev SR, Chemodanov IG. Complications of blood donation and transfusion. M.: Pirogov National Medical and Surgical Center, 2019. (In Russ.)

8. Pokhabov DS, Fomina AYu, Shestakov EA, Zhiburt EB. Erythrocyte antigen KEL1 in a new form of case history. Astrakhanskii medicinskii zhurnal. 2023; 18(4): 6-10. (In Russ.) doi: 10.17021/1992-6499-2023-4-6-10.

9. Zhiburt EB, Shestakov EA, Kuznetsov S.I. Hemolytic transfusion reactions. Vestnik Nacional’nogo mediko-hirurgicheskogo centra im. N.I. Pirogova. 2019; 14(4): 105-111. (In Russ.) doi: 10.25881/ BPNMSC.2020.17.22.020.

For citation

Zarubin M.V., Zaznobov M.E., Kuvshinova V.A., Ihiseeva L.V., Agapitov E.A., Yankova T.S., Senderova O.M., Zhiburt E.B. Hemolysys during plasmapheresis with a deficiency of glucose-6-phosphate dehydrogenase. Bulletin of Pirogov National Medical & Surgical Center. 2026;21(1):170-172. (In Russ.) https://doi.org/10.25881/20728255_2026_21_1_170