Authors
Filippov V.M., Korobov E.N., Telyatov B.A.
M.M. Krasnov Research Institute of Eye Diseases, Moscow
Abstract
Background. Postoperative cystoid macular edema (CME) is a complication of surgical treatment of various eye diseases and is caused by the development of an aseptic inflammatory reaction. The lack of a universal treatment regimen for CME necessitates the development of therapeutic methods for this complication. The objective of this study was to evaluate the clinical efficacy of a combination anti-inflammatory treatment regimen for postoperative CME.
Material and Methods. This study presents a series of 8 clinical cases. All patients received treatment according to the developed regimen using steroidal and non-steroidal anti-inflammatory drops.
Results. In all cases, improvements in visual function and retinal anatomical condition were achieved.
Conclusion. The proposed CME treatment regimen has demonstrated efficacy and is recommended for use and further study in a larger sample of patients.
Keywords: cystoid macular edema, Irine-Gass syndrome, non-steroid anti-inflammatory drugs, fluorometholone acetate.
References
1. Budzinskaya M.V., Plyukhova A.A. Future Perspectives for Antiangiogenic Therapy in Retinal Diseases. Ophthalmology in Russia. 2021;18(3S):638-645. (In Russ.) doi.org/10.18008/1816-5095-2021-3S-638-645.
2. Sakalova ED, Avetisov KS, Budzinskaia MV, Andreeva IV. Pathogenesis and diagnostics of postsurgical macular edema. Russian Annals of Ophthalmology. 2018;134(1):107‑112. (In Russ.) doi.org/10.17116/oftalma20181341107-112.
3. Avetisov KS, Yusef YuN, Smirnova TV, Sakalova ED, Avetisov SE. Morphological and functional condition of the macula after different types of phaco cataract surgeries. Russian Annals of Ophthalmology. 2020;136(1):4‑16. (In Russ.) doi.org/10.17116/oftalma20201360114.
4. Budzinskaya MV, Plyukhova AA, Alkharki L. Modern trends in anti-VEGF therapy for age-related macular degeneration. Russian Annals of Ophthalmology. 2023;139(3‑2):46‑50. (In Russ.) doi.org/10.17116/oftalma202313903246.
5. Sakalova ED. Modern approaches to treatment of postsurgical macular edema. Russian Annals of Ophthalmology. 2020;136(4):289‑295. (In Russ.) doi.org/10.17116/oftalma2020136042289.
6. Petrachkov D.V., Antonov A.A., Bobkova A.S., Baryshev K.V., Agadzhanyan T.M. Comparative analysis of the effect of anti-inflammatory therapy on ophthalmotonus in patients with vitreoretinal pathology in the early postoperative period. Ophthalmosurgery. 2024;4(142): 48–54. doi: 10.25276/0235-4160-2024-4-48-54.
7. Fayzrakhmanov R.R., Voropaev V.Yu., Sukhanova A.V., Shatalova E.O. Antiangiogenic therapy of neovascular age-related macular degeneration. Vestnik ofhtalmologii. 2021;137(1):83 93. doi.org/10.17116/oftalma202113701183.
