DOI: 10.25881/20728255_2025_20_4_S1_4

Authors

khodzhaev N.S., Sorokoletov G.V., Kolysheva O.S., Taevere M.R.

S.N. Fedorov NMRC “MNTK “Eye Microsurgery”, Moscow

Abstract

Objective. To evaluate the efficacy and safety of a combined surgical approach in patients with primary open-angle glaucoma and cataract complicated by grade I–II lens subluxation in the setting of pseudoexfoliation syndrome.

Materials and methods. The study included 40 patients (40 eyes) with POAG stages II–III, cataract, and grade I–II lens subluxation associated with PEX. All patients underwent simultaneous combined surgery: phacoemulsification with IOL implantation using the optic capture technique and non-penetrating deep sclerectomy with implantation of a Healaflow collagen drain.

Results. At 12 months after surgery, a significant improvement in uncorrected visual acuity (UCVA) was observed: from 0.12±0.04 to 0.38±0.06 in stage II glaucoma and from 0.04±0.02 to 0.40±0.08 in stage III glaucoma (p<0.001). Intraocular pressure (IOP) decreased to 16.4±2.1 mmHg and 17.0±1.9 mmHg, respectively (p<0.001). Antihypertensive therapy was discontinued in 85% of patients with stage II and 80% with stage III glaucoma.

Conclusion. Combined surgical treatment demonstrated high efficacy and safety in patients with this complex ocular pathology.

Keywords: cataract; glaucoma; lens subluxation; pseudoexfoliation syndrome; combined surgery; non-penetrating deep sclerectomy.

References

1. Tham Y.-C., Li X., Wong T.Y., Quigley H.A., Aung T., Cheng C.-Y. Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040: A Systematic Review and Meta-Analysis // Ophthalmology. – 2014. – Vol. 121, № 11. – P. 2081–2090.

2. Ivachev E.A. Causes of cataract progression in glaucoma patients (report 2). National Journal glaucoma. 2025;24(1):58-64. (In Russ.)

3. World report on vision. – Geneva: World Health Organization, 2023.

4. Ivachev E.A. Kochergin S.A., Ivacheva O.T. Method of intraocular lens fixation in patients with compensated glaucoma and cataract complicated by zonular weakness. (In Russ.)

5. Pashtaev N.P., Kulikov I.V. Subluxated cataract surgery. (In Russ.)

6. Desai M.A., Lee R.K. The medical and surgical management of pseudoexfoliation glaucoma // Int Ophthalmol Clin. – 2008. – Vol. 48, № 4. – P. 95–113.

7. Kulikov A.N., Churashov S.V., Danilenko E.V., Shamrey D.V., Kondratov V.S. Comparative Analisys of Cataract Phakoemulsification, Complicated with the Zonular Weakness. Ophthalmology in Russia. (In Russ.)

8. Firas Ben Amor , Sineok A.E., Zhukova O.V. , Malov V.M., Eroshevskaya E.B. Methods of intraocular lens fixation in complicated cases of lens surgery. (In Russ.)

9. Yamane S., Sato S., Maruyama-Inoue M., Kadonosono K. Flanged Intrascleral Intraocular Lens Fixation with Double-Needle Technique // Ophthalmology. – 2017. – Vol. 124, № 8. – P. 1136–1142.

10. Anisimov S.I., Anisimova S.Y., Arutyunyan L.L., Voznyuk A.P.,Anisimova N.S. Modern approaches to surgical treatment of combined pathology of glaucoma and cataract. (In Russ.)

For citation

khodzhaev N.S., Sorokoletov G.V., Kolysheva O.S., Taevere M.R. Efficacy and Safety of Combined Cataract and Glaucoma Surgery in Patients with Lens Subluxation and Pseudoexfoliation Syndrome. Bulletin of Pirogov National Medical & Surgical Center. 2025;20(4,supplement):4-7. (In Russ.) https://doi.org/10.25881/20728255_2025_20_4_S1_4