DOI: 10.25881/20728255_2025_20_3_64

Authors

Lavreshin P.M.1, Gobejishvili V.K.1, Gobedzhishvili V.V.2, Korablina S.S.1, Chotchaev M.K.1, Chumakov P.I.1, Uzdenov M.A.1

1 Stavropol State Medical University, Stavropol

2 I.M. Sechenov First Moscow State Medical University, Moscow

Abstract

Rationale: The incidence of acute appendicitis is 708 cases per 10000 population. Postoperative complications after open appendectomy were 2.35 to 10%, after laparoscopic appendectomy from 4.9% to 6.2%. Abdominal interventions are accompanied by the development of intra-abdominal adhesions in 14.0% of patients, after repeated interventions – in 90.0-96.0% of the operated patients.

Purpose: To determine the efficacy of anti-adhesion therapy after appendectomy.

Materials and methods: 60 patients with acute appendicitis who underwent open appendectomy. Men – 19 (31.7%), women – 41 (68.3%). The control group consisted of 30 (50%) patients who did not undergo prevention of intra-abdominal adhesions in the postoperative period, and another 30 (50%) patients who received anti-adhesion therapy (main group). To calculate the risk of intra-abdominal adhesions after appendectomy, we have developed an “Assistant program for determining the effectiveness of the treatment method and preventing the development of postoperative intra-abdominal adhesions”.

Results: By the method of rating testing, it was established that the highest risk of developing postoperative intra-abdominal adhesions is present in patients who do not receive a set of anti-adhesion measures. Anti-adhesion therapy in patients after appendectomy reduces the risk of intra-abdominal adhesions by 1.97 times, improves the quality of life of operated patients.

Conclusion: When performing abdominal operations, it is necessary to form groups of patients with a tendency to the formation of intra-abdominal adhesions, for whom anti-adhesion therapy is indicated in order to reduce the risk of developing an adhesive process in the abdominal cavity.

Keywords: acute appendicitis, appendectomy, prognosis, intra-abdominal adhesions, prophylaxis.

References

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7. Certificate №2024680628/30.08.24. Uzdenov MA, Lavreshin PM, Gobezhishvili VK, et al. Certificate of State Registration of a Computer Program. Program-assistant for determining the effectiveness of a treatment method in prevention of postoperative intra-abdominal adhesions. (In Russ.)

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For citation

Lavreshin P.M., Gobejishvili V.K., Gobedzhishvili V.V., Korablina S.S., Chotchaev M.K., Chumakov P.I., Uzdenov M.A. Personalized approach to the prognosis and prevention of intra-abdominal adhesions after appendectomy. Bulletin of Pirogov National Medical & Surgical Center. 2025;20(3):64-68. (In Russ.) https://doi.org/10.25881/20728255_2025_20_3_64