The effect of the antiseptic coating with miramistin on the strength and extensibility of the suture material

Sukovatykh B.S., Nazarenko P.M., Mosolova A.V., Pashkov V.M.

Relevance. The failure of the intestinal suture in conditions of widespread peritonitis ranges from 10% to 20%. One of the promising directions of prevention is the use of suture material with an antiseptic coating.

The purpose of the study. To study the effects of the seam material coated with miramistin on the strength and extensibility of polyglycolide thread.

Materials and methods. Samples of an inert polyglycolide absorbable filament and a filament coated with 20% miramistin from the total polymer mass were examined. Two series of experiments with 10 samples each were carried out. In the first (control) series, the mechanical properties of an inert filament were studied, and in the second — with a 20% antiseptic coating. The thread samples were immersed in a phosphate buffer solution (pH 7.4), with a constant temperature of 37° C in the thermostat. The thread was examined on the 1st, 3rd, 7th, 14th and 21st days of the experiment. Samples of suture material were stretched to rupture on a universal testing bursting machine. The physico-mechanical properties were evaluated by the dynamics of the indicators of the breaking load and its breaking elongation in a simple node.

Results. On the 1st day of the experiment, the strength of the antiseptic-coated thread exceeded the inert thread by 1.15, by the 3rd by 1.14, by the 7th by 1.2, by the 14th by 1.17, by the 21st by 1.18 times.

The tension at the thread break in the samples of threads coated with miramistin in the experimental group decreased by 4.1% compared to the inert thread on day 1; by 3.73% on day 3; by 3.1% on day 7, by 1.16% on day 14; there were no differences on day 21.

Conclusion. Coating the suture material with miramistin leads to an increase in strength and a decrease in the extensibility of the suture material.

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