DOI: 10.25881/20728255_2023_18_4_S1_17

Authors

Sekhina O.L. 2, Konovalova K.I.1, 2, Fayzrakhmanov R.R.1, 2, Vaganova E.E.2

1 N.I. Pirogov National Medical Surgical Center, Moscow

2 Institute of Advanced Training of Physicians N.I. Pirogov National Medical Surgical Center, Moscow

Abstract

Purpose: To evalute the efficacy of short-term tamponade of the vitreal cavity by perfluorinated compound in patients with retinal regomatogenic detachment when localizing a tear in the lower part of the retina.

Material and methods: The analysis of surgical treatment of 30 patients with the diagnosis of primary regmatogenic retinal detachment in combination with proliferative vitreoretinopathy с type 1-3 with inclusion of the macular zone, with the localization of the rupture in the lower retina. All patients were divided into two groups depending on the tamponade vitreal cavity. I group (n = 14): first stage – vitreoretinal surgery with a tamponade of the vitreal cavity of perfluoroorganic compounds for 14 days, second stage – removal of perfluoroorganic compounds from the vitreal cavity + facoemulsification with implantation of the intraocular lens + tamponade of the natural gas mixture (С2F6). Monitoring for at least 6 months after perfluorinated compound or silicone oil removal.

Results: The preliminary results of the study showed a high effectiveness of short-term perfluorinated compound tamponade compared to the silicone oil tamponade in patients with retinal regomatogenic detachment at the localization of a tear in the lower retina, relapse was detected only in the ii group of 37,5% of the cases. Conclusion. The results of the conducted study confirm the effectiveness of the use of short-term tamponade of the vitreal cavity of perfluorinated compound in the treatment of patients with retinal detachment at the localization of a tear in the lower retina. This method improves the anatomical and functional results of vitreoretinal surgery in this category of patients and helps to reduce the number of postoperative complications.

Keywords: rhegmatogenous retinal detachment, tamponade of the vitreal cavity, perfluoroorganic compound.

References

1. Obshcherossiiskaya obshchestvennaya organizatsiya “Assotsiatsiya vrachei-oftalmologov”. Federalnye klinicheskie rekomendatsii “Regmatogennaya otsloika setchatki”. 2017. p.5 (In Russ.)

2. Sheng Y, Sun W, Mo B, et. al. Non-buckled vitrectomy for retinal detachment with inferior breaks and proliferative vitreoretinophathy. Int J Ophthalmol. 2012;5(5):591-5. doi: 10.3980/j.issn.2222-3959.2012.05.09.

3. Boscia F, Furino C, Recchimurzo N, et. al. Oxane HD vs silicone oil and scleral buckle in retinal detachment with proliferative vit reoretinopathy and inferior retinal breaks. Graefes Arch Clin Exp Ophthalmol. 2008;246(7):943–948. doi: 10.1007/s00417-008-0806-7

4. Foster RE, Meyers SM. Recurrent retinal detachment more than 1 year after reattach ment. Ophthalmology. 2002;109:1821–1827. doi: 10.1016/S0161-6420(02)01182-X

5. Mitry D, Singh J, Yorston D, et. al. The predisposing pathology and clinical characteristics in the Scot tish Retinal Detachment Study. Ophthalmology. 2011;118(7):1429–1434. doi: 10.1016/j.ophtha.2010.11.031

6. Barthelmes D, Chandra J. Perfluoro-n-octane as a temporary intraocular tamponade in a staged approach to manage complex retinal detachments. Clin Ophthalmol. 2015;9:413-8. doi: 10.2147/OPTH.S76947. PMID: 25784785; PMCID: PMC4356446.

7. Sargent JW, Seffl RJ. Properties of perfluorinated liquids. Fed Proc. 1970;29(5):1699-703. PMID: 5457573

8. Lukovskaya NG, Astakhov YuS, Sajgina EA. The analysis of frequency and causes of recurrent retinal detachment after the external steps of surgical treatment. Ophthalmology Reports. 2010; 3(4):24-28. (In Russ.)

9. Shevalova TN, Churashov SV, Kulikov AN. Retinotomy versus encircling scleral buckling in the vitroretinal surgery for recurrent inferior rhegmatogenous retinal detachment in silicone oil-filled eyes. Vestnik Oftalmologii. 2022;17(4). (In Russ.) doi:10.25881/20728255_2022_17_4_S1_28[2].

10. Arslanov GM, Aznabaev ВM, Mukhamadeev TR, et. al. Evidence of the safe period intravitreal tamponade by perfluorodecalin in clinical practice. Saratov Jornal of Medical Scientific Research 2018; 14(4):862-866. (In Russ.)

11. Keller J, Govetto A, Ramasamy P, et. al. Comparison of perfluorodecalin and silicone oil as initial tamponade for giant tetinal tear-associated retinal detachment. Ophthalmologica. 2021; 244(3):218-222. doi: 10.1159/ 000516520.

12. Mikhail VA, Mangioris G, Best RM, et. al. Management of giant retinal tears with vitrectomy and perfluorocarbon liquid postoperatively as a short-term tamponade. Eye (Lond). 2017; 31(9):1290-1295. doi:10.1038/eye.2017. 157.

13. Rofail M, Lee LR. Perfluoro-n-octane as a postoperative vitreoretinal tamponade in the management of giant retinal tears. Retina. 2005 Oct-Nov;25 (7):897-901. doi: 10.1097/00006982-200510000-00013.

14. Dravica LV, Biryukov FI, Rudakevich VV, et. al. Vtorichnaya glaukoma na glazah s silikonovoj tamponadoj vitreal’noj polosti. In: Sbornik tezisov po materialam nauchno – prakticheskoj konferencii «Sovremennye tekhnologii lecheniya vitreoretinal’noj patologii»; Moscow 19-20 March 2009. Moscow. (In Russ.)

15. Litvinchuk LM. Chastota i prichiny razvitiya vtorichnoj glaukomy pri silikonovyh endotamponadah na glazah s oslozhnennoj miopiej vysokoj stepeni. Sbornik tezisov nauchno-prakticheskoj konferencii. «Sovremennye tekhnologii lecheniya vitreoretinal’noj patologii»; Moscow 22-23 March 2012. p. 115. (In Russ.)

16. Loskutov IA, Manaenkov KI. Factors of Development of Secondary Silicone-Induced Glaucoma and Their Consequences (Literature Review). Ophthalmology 2022; 18 (45): 30–37. (In Russ.) doi:10.33978/2307-3586-2022-18-45-30-37

17. Shishkin MM, Kocheva EA, Fayzrakhmanov RR. Episcleral circular buckling in surgical treatment of recurrent rhegmatogenous retinal detachment after vitrectomy. Russian Annals of Ophthalmology = Vestnik oftal’mologii. 2022;138(6):65–69 [URL] (InRuss.)

.18. Oliveira-Ferreira C, Azevedo M, Silva M, et. al. Unexplained Visual Loss After Silicone Oil Removal: A 7-Year Retrospective Study. Ophthalmol Ther. 2020;9(3):1-13. doi: 10.1007/s40123-020-00259-5.

19. Fayzrakhmanov RR, Sukhanova AV, Shishkin MM, et. al. Changes in perfusional and morphological parameters of the macular area after silicone oil tamponade of the vitreous cavity.Vestnik Oftalmologii. 2020;136(5):46 51 [URL] (In Russ.)

20. Fayzrakhmanov RR, Sukhanova AV, Larina EA, et. al. Dynamics of the perfusion foveolar parameters after silicone oil tamponade due to regmatogenic retinal detachment (macula-off). Medline.ru. Russian Biomedical Journal.2020; 21(5):44-54. (In Russ.)

For citation

Sekhina O.L. , Konovalova K.I., Fayzrakhmanov R.R., Vaganova E.E. Comparative analysis of surgical treatment of rhegmatogenous retinal detachment with lower localization of breaks. Bulletin of Pirogov National Medical & Surgical Center. 2023;18(4,supplement):17-21. (In Russ.) https://doi.org/10.25881/20728255_2023_18_4_S1_17