Authors
Khanevich M.D.1, 2, Perminova A.A.1, Manikhas G.M.3, Giparovich M.A.2, Yuryev E.Y.2
1 Saint Petersburg State Pediatric Medical University, St. Petersburg
2 Russian Research Institute of Hematology and Transfusiology, St. Petersburg
3 First St. Petersburg State Medical University named after Academician I.P. Pavlova, St. Petersburg
Abstract
To date, there has been no consistent position on the rationale for blood transfusions in surgical patients. Randomized clinical studies on this problem have provided inconsistent data, which distinguished restrictive (restrictive) and liberal (non-restrictive) strategies of blood transfusion. The aim of the study was to analyze the data obtained by domestic and foreign authors on the study of indications for transfusion of donor erythrocytes in surgical patients, as well as to analyze our own observations. Research methods included an analysis of indications for transfusion of donor red blood cells in patients divided into three groups: the first group consisted of patients with ongoing bleeding caused by trauma and injuries of various localizations; the second group consisted of patients who underwent extended and combined operations on the chest and abdominal organs; the third group included patients with gastroduodenal profuse bleeding. There were 300 patients in total who were analyzed (100 patients in each group). The result of the study was to substantiate the use in clinical practice of both restrictive and liberal strategies of donor erythrocyte transfusion. It has been established that in cases of wounds and injuries and also at planned operations advantage should be given to the liberal strategy, at gastroduodenal bleedings - to restrictive one. Reducing the volume of hemotransfusions is possible with the widespread introduction into clinical practice of minimally invasive interventions to stop bleeding.
Keywords: transfusion, donor erythrocytes, restrictive strategy, liberal strategy.
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