DOI: 10.25881/20728255_2022_17_4_2_46


Аntonov A.A. 1, Reshetnikova V.V.2, Dolzhikova Yu.I.2, Solod E.I.1, Lazarev A.F.1, Antonov A.K.3, Gorenkov R.V.3, Simonova A.V.3, Talipov I.A.4

1 N.N. Priorov National Medical Research Center of Traumatology and Orthopedics, Moscow

2 N.N. Blokhin National Medical Research Center of Oncology, Moscow

3 Moscow Regional Research and Clinical Institute («MONIKI»), Moscow

4 Medical College No. 7, Moscow


Rationale: In order to predict postoperative infectious complications in patients and their prevention, it is very important to study the markers of inflammation when performing total hip replacement with long-standing trochanter fractures of the femur.

Objective: Study of the inflammation markers dynamics in patients with total hip arthroplasty and old trochanteric fractures in the postoperative period.

Methods: clinical, laboratory, ELISA, statistics.

Results: In patients with postoperative complications elevated levels of C-reactive protein, erythrocyte sedimentation rate and pro-inflammatory cytokines are recorded.

Conclusion: As a result of the studies, it was revealed that the risk factors for the development of postoperative complications are advanced and senile age, comorbid disease and smoking. Elevated levels of C-reactive protein, erythrocyte sedimentation rate, leukocytosis and serum IL-6 may be regarded as significant predictors of inflammatory events in the postoperative period. High levels of IL-8 in the blood suggestive of the manifestations of infectious complications.

Keywords: total hip arthroplasty; inflammation markers; cytokines; old trochanteric fracture.


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For citation

Аntonov A.A. , Reshetnikova V.V., Dolzhikova Yu.I., Solod E.I., Lazarev A.F., Antonov A.K., Gorenkov R.V., Simonova A.V., Talipov I.A. Inflammatory markers in the early postoperative period in patients who underwent total hip replacement with long-standing trochanter fractures of the femur. Bulletin of Pirogov National Medical & Surgical Center. 2022;17(4-2):46-50. (In Russ.)