DOI: 10.25881/20728255_2022_17_3_33

Authors

Maklagina A.V., Zhbanov I.V., Shabalkin B.V.

Petrovsky National Research Centre of Surgery, Moscow

Abstract

Objective. to compare the long-term results of surgical treatment of patients with coronary heart disease and concomitant lesions of the carotid arteries on a beating heart and under cardiopulmonary bypass.

Materials and methods. The work is based on a prospective analysis of the results of surgical treatment of 143 patients who underwent a combined intervention - coronary bypass surgery and carotid endarterectomy. The patients were divided into two groups depending on the type of intervention: 74 (51.7%) patients operated on a working heart without cardiopulmonary bypass and 69 (48.3%) operated under conditions of cardiopulmonary bypass.

Results. An analysis of the duration and quality of life of patients within 5 years after simultaneous operations on the carotid and coronary arteries on a beating heart showed a high survival rate (90.1%) with a rather low incidence of myocardial infarction - 4.6% and acute cerebrovascular accident - 3.8 % for the specified observation period. There were no significant differences in the annual dynamics of survival and rates of “freedom from the listed complications” after combined operations on a beating heart and under cardiopulmonary bypass. However, the combined rate of adverse cardiovascular events MACCE (recurrent angina, myocardial infarction, acute cerebrovascular accident, death) was significantly lower after simultaneous operations without cardiopulmonary bypass (11.6% vs. 25.8%, p = 0.043).

Conclusion. Simultaneous coronary artery bypass grafting without cardiopulmonary bypass and carotid endarterectomy provide a high quality of life for operated patients in the long-term period, are accompanied by low mortality, as well as a lower complication rate.

Keywords: coronary artery disease, carotid endarterectomy, coronary artery bypass grafting, myocardial revascularization on a beating heart without cardiopulmonary bypass.

References

1. Gaudino M, Glieca F, Alessandrini F, Nasso G, Pragliola C, Luciani N, Morelli M, Possati G. High risk coronary artery bypass patient: incidence, surgical strategies, and results. The annals of thoracic surgery. 2004; 77(2): 574-579. doi: 10.1016/S0003-4975(03)01534-0.

2. Steinvil A, Sadeb B, Arbel Y, Justo D, Belei A, Borenstein N, et al. Prevalence and predictors of concomitant carotid and coronary artery atherosclerotic disease. Journal of the American College of Cardiology. 2011; 57: 779-783. doi: 10.1016/j.jacc.2010.09.047.

3. Ivanov SV, Sumin AN, Kazachek YaV, Filip’ev DE, Gusev SM, Malyshenko ES, Barbash LS. Options for revascularization outcomes optimization in patients with polyvascular disease. Kompleksnye problemy serdechno-sosudistykh zabolevanii. 2013; 3: 26-35. (In Russ).

4. Bernhard VM, Johnson WD, Peterson JJ. Carotid artery stenosis. Association with surgery for coronary artery disease. Arch Surg. 1972; 105: 837-840. doi: 10.1001/archsurg.1972.04180120018005.

5. Okies JE, MacManus Q, Starr A. Myocardial revascularization and carotid endarterectomy: a combined approach. The annals of thoracic surgery. 1977; 23(6): 560-563. doi: 10.1016/s0003-4975(10)63702-2.

6. Zhbanov IV, Sidorov RV, Kiladze IZ, Uriuzhnikov VV, Molochkov AV. Selection of the optimal methods of coronary artery bypass surgery in patients with high risk. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2014; 7(2): 15-18. (In Russ).

7. Perez-Vela JL, et al. Neurologic complications in the immediate postoperative period after cardiac surgery. Role of brain magnetic resonance imaging. Rev. Esp. Cardiol. 2005; 58(9): 1014-1021. doi: 10.1157/13078548.

8. Buziashvili YuL, Ambatiello SG, Alexakhina YuA, Pashchenkov MV. Influence of cardiopulmonary bypass on cognitive functions in patients with ishemic heart disease. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2005; 1: 150-157. (In Russ).

9. Shneider YuA, Tsoi VG, Pavlov AA. Immediate and intermediate results of staged carotid endarterectomy in combination with coronary bypass grafting. Angiology and vascular surgery. 2019; 25(3): 95-99. (In Russ). doi: 10.33529/ANGIO2019304.

10Myalyuk PA, Marchenko AV, Arutyunyan VB, Chragyan VA, Alekseevich GYu, Vronskii AS. Prevention of cerebrovascular complications in coronary bypass grafting. Angiology and vascular surgery. 2017; 23(2): 148-156. (In Russ).

11. Silaev AA, Kondaurov AE, Chvokov AV, Zorin EV, Nazaryan KE, Doronkin DA, Peshcherenkova KA, Luchkin AV. Current aspects of surgical treatment of patients with coronary heart disease. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2014; 7(6): 24-27. (In Russ).

12. Bazylev VV, Chernogrivov AE, Voevodin AB. Simultaneous interventions on carotid and coronary arteries: what is the risk due to? Angiology and vascular surgery. 2012; 18(3): 106-115. (In Russ).

13. Zhbanov IV, Maklagina AV, Uriuzhnikov VV, Shabalkin BV. Off-Pump coronary artery bypass grafting in simultaneous surgical treatment of patients with concomitant atherosclerotic lesion of coronary and supra-aortic arteries. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2022;15(2):114–121. (In Russ). doi:10.17116/kardio202215021114

14. Russian Society of Angiologists and Vascular Surgeons. National guidelines for the management of patients with diseases of the brachiocephalic arteries. 2013;19–20. (In Russ).

15. Dzierwa K, Pieniazek P, Musialek P, Piatek J, Tekieli L, Podolec P, et al. Treatment strategies in severe symptomatic carotid and coronary artery disease. Med Sci Monit. 2011;17:191–197. doi: 10.12659/MSM.881896

16. Bokeriya LA, Sigaev IYu, Darvish NA, Ozolin’sh AA, Eseneev MF, Mollaev EB, et al. Treatment tactics for patients with concomitant atherosclerotic lesions of the brachiocephalic and coronary arteries. ZHurnal Nevrologii I Psihiatrii Im Cc Korsakova. 2016;2:22–28. (In Russ). doi: 10.17116/jnevro20161162122-28

17. Voznyuk IA, Arsenova NA, Hubulava GG. Cerebral complications of coronary artery bypass graft surgery. Rossiiskii biomeditsinskii zhurnal. 2009;10:150–159. (In Russ.)

18. Belov YuV, Komarov RN. Tactics of surgical treatment of multifocal stenotic lesions. Pirogov Russian journal of surgery. 2007; 3: 64-66. (In Russ).

19. Shabalkin BV, Zhbanov IV, Molochkov AV. Combined operations on coronary and brachiocephalic arteries: surgical tactics and results. Annaly hirurgii. 2002; 3: 46-49. (In Russ).

20. Sharma V, Deo SV, Park SJ, Joyce LD. Meta-analysis of staged versus combined carotid endarterectomy and coronary artery bypass grafting. The annals of thoracic surgery. 2014; 97(1): 102-109. doi: 10.1016/j.athoracsur.2013.07.091.

21. Molochkov AV, Muradov MM, Kiladze IZ, Zhbanov IV, Shabalkin BV. Surgical treatment of advanced age patients with concomitant atherosclerotic lesion of coronary and brachiocephalic arteries. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2015; 8(5): 26-30. (In Russ). doi: 10.17116/kardio20158526-30.

22. Bulat C, et al. Combined surgical approach to carotid and coronary artery disease. Collegium antropologicum. 2008; 32(1): 209-216.

For citation

Maklagina A.V., Zhbanov I.V., Shabalkin B.V. Long-term results of surgical treatment of patients with combined atherosclerotic lesions of the coronary and carotid arteries. Bulletin of Pirogov National Medical & Surgical Center. 2022;17(3):33-37. (In Russ.) https://doi.org/10.25881/20728255_2022_17_3_33