DOI: 10.25881/20728255_2022_17_3_23

Authors

Zhbanov I.V., Kiladze I.Z., Uryuzhnikov V.V., Martirosyan A.K., Shabalkin B.V.

B.V. Petrovsky Russian Research Center of Surgery, Moscow

Abstract

Rationale: CABG is the gold standard of treatment for coronary artery disease. Surgery as a whole is based on the desire to optimize its results, which can be achieved by minimizing the traumatism of this operation. And in particular, the use of new minimally invasive methods is preferable with an increased risk of complications associated with artificial blood circulation, sternotomy and manipulation on the aorta.

Objective: to compare the immediate results of patients operated according to the classical method through median sternotomy and patients operated through left-sided mini-thoracotomy, and to identify the advantages of one method over the other.

Methods: The study group consisted of 90 patients who underwent CABG via left-sided mini-thoracotomy (group A). Control group B included 104 patients after isolated CABG via median sternotomy. The average age of patients was 63,8±7,2 years in group A and 59,9±8,1 years in group B. The body mass index in group A was 28,2±4,3 kg/m2 and in group B 31,2±4 kg/m2. All patients were diagnosed with multivessel CA lesion. The average left ventricular ejection fraction (LV EF) was 58,2±9,9% in group A and 55,7±9,1% in group B. In group A 27,8% patients and 39,4% in group B had previously performed coronary angioplasty.

Results: The difference in the average duration of minimally invasive (251±88 min) and traditional (243±62,2 min) CABG was unreliable. The majority of patients in both groups operated without CPB — 92,5% in group A and 89,4% in group B. The revascularization index in the study groups was 2,6±0,9 and 3,1±0,85. The complex and longer harvesting of two IMA through a mini-step at the stage of mastering MICS CABG technology explains the less frequently performed BIMA CABG in group A (41,3%) compared to group B (71,1%, p<0,05). Both intraoperative (283±92 ml vs. 527±172,2 ml) and postoperative drainage blood loss (205±50 vs. 350±46 ml) was significantly less in group A. Patients after minimally invasive CABG were more quickly transferred to independent breathing (mean ventilator time 123±38,1 min vs. 274,4±62,8 min after traditional CABG, p<0,05). In the absence of significant differences in the duration of stay in cardiac intensive care, patients returned home faster after minimally invasive CABG (7,1±2,1 days after surgery versus 8,5±2,2 days in group B, p<0,05).

Conclusion: The results obtained show that multiple CABG via left mini-thoracotomy is not accompanied by an increase in the frequency of perioperative complications and an increase in hospital mortality. Already at the stage of mastering such operations, it becomes obvious that MICS CABG technology in most patients does not limit the required volume of surgery, and as experience accumulates, it allows using two IMA to achieve autoarterial myocardial revascularization. Lesion LCA, a disabled myocardium with a moderate decrease in LV contractility do not exclude the possibility of performing CABG through a mini-thoracotomy. In such cases, there is always a risk of developing acute myocardial ischemia and severe hemodynamic disorders with dislocation of the heart can be eliminated through the use of peripheral CPB.

Keywords: CABG, left-sided mini-thoracotomy, BIMA CABG.

References

1. Benetti FJ, Ballester C. Use of thoracoscopy and a minimal thoracotomy, in mammary-coronarybypasstoleftanteriordescendingartery,withoutextracorporeal circulation. Experience in 2 cases. J Cardiovasc Surg (Torino) .1995; 36(2): 159-61.

2. Subramanian VA. Clinical experience with minimally invasive reoperative coronary bypass surgery. Eur J Cardiothorac Surg. 1996; 10(12): 1058-62.

3. McGinn Joseph T, Usman S, Lapierre H, Pothula VR, Mesana TG, Ruel M. Minimally Invasive Coronary Artery Bypass Grafting. Circulation. 2009; 120(11): 78-S84.

4. Benedetto U, Angelini GD, Caputo M, Feldman DN, Kim LK, Lau C, et al. Off- vs. on-pump coronary artery bypass graft surgery on hospital outcomes in 134, 117 octogenarians. J Thorac Dis. 2017; 9(12): 5085-92.

5. Hoff SJ, Ball SK, Leacche M, Solenkova N, Umakanthan R, Petracek MR, et al. Results of completion arteriography after minimally invasive off-pump coronary artery bypass. Ann Thorac Surg. 2011; 91: 31-6.

6. Ruel M, Shariff MA, Lapierre H, Goyal N, Dennie C, Sadel SM, et al. Results of the minimally invasive coronary artery bypass grafting angiographic patency study. J Thorac Cardiovasc Surg. 2014; 147: 203-8.

7. Ruel M, Une D, Bonatti J, McGinn JT. Minimally invasive coronary artery bypass grafting: is it time for the robot? Curr Opin Cardiol. 2013; 28(6): 639-45.

8. Birla R, Patel P, Aresu G, Asimakopoulos G. Minimally invasive direct coronary artery bypass versus off-pump coronary surgery through sternotomy. Ann R Coll Surg Engl. 2013; 95(7): 481-485. doi: 10.1308/003588413X13629960047119.

9. Hirata N, Sawa Y, Takahashi T, Katoh H, Ohkubo N, Matsuda H. Is median sternotomy invasive? A comparison between minimally invasive direct coronary artery bypass and off-pump bypass. Surg Today. 2000; 30(6): 503-505. doi:10.1007/s005950070115.

10. Raja SG, Benedetto U, Alkizwini E, Gupta S, Amrani M, Harefield Cardiac Outcomes Research Group. Propensity Score Adjusted Comparison of MIDCAB Versus Full Sternotomy Left Anterior Descending Artery Revascularization. Innov Phila Pa. 2015; 10(3): 174-178. doi:10.1097/IMI.0000000000000162 309.

11. Tekin Aİ, Arslan Ü. Perioperative outcomes in minimally invasive direct coronary artery bypass versus off-pump coronary artery bypass with sternotomy. Wideochirurgia Inne Tech Maloinwazyjne Videosurgery Miniinvasive Tech. 2017; 12(3): 285-290. doi:10.5114/wiitm.2017.67679.

12. Xu Y, Li Y, Bao W, Qiu S. MIDCAB versus off-pump CABG: Comparative study. Hell J Cardiol HJC Hell Kardiologike Epitheorese. Published online January 25, 2019. doi:10.1016/j.hjc.2018.12.004.

13. TSCoJAfCAS. Coronary artery surgery results. [URL] Japanese Association for Coronary Artery Surgery. 2016.

14. Saito A, Hirahara N, Motomura N, Miyata H, Takamoto S. Current status of cardiovascular surgery in Japan, 2013 and 2014: Areport based on the Japan Cardiovascular Surgery Database 3. Coronary artery bypass surgery. Gen Thorac Cardiovasc Surg. 2018; 66(1): 8-12.

15. Bakaeen FG, Kelly RF, Chu D, Jessen ME, Ward HB, Holman WL. Trends over time in the relative use and associated mortality of on-pump and off-pump coronary artery bypass grafting in the Veterans Affairs system. JAMA Surg. 2013; 148(11): 1031-6.

16. Beckmann A, Funkat AK, Lewandowski J, Frie M, Ernst M, Hekmat K, et al. German heart surgery report 2016: the annual updated registry of the german society for thoracic and cardiovascular surgery. Thorac Cardiovasc Surg. 2017; 65(7): 505-18.

17. Chan V, Lapierre H, Sohmer B, Mesana TG, Ruel M. Handsewn proximal anastomoses onto the ascending aorta through a small left thoracotomy during minimally invasive multivessel coronary artery bypass grafting: a stepwise approach to safety and reproducibility. Semin Thorac Cardiovasc Surg 2012; 24: 79-83.

18. Lapierre H, Chan V, Sohmer B, Mesana TG, Ruel M. Minimally invasive coronary artery bypass grafting via a small thoracotomy versus off-pump: a case-matched study. Eur J Cardiothorac Surg. 2011; 40(4): 804-10.

19. Ziankou AА. Early and late results of no-touch aorta multivessel minimally invasive coronary artery bypass grafting: a propensity score-matched study. Clin. Experiment. Surg. Petrovsky J. 2018; 1(19): 10-20. (In Russ).

20. King RC, Reece TB, Hurst JL, et al. Minimally invasive coronary artery bypass grafting decreases hospital stay and cost. Ann Surg. 1997; 225(6): 805-9 [discus-

sion: 809-11].

21. Lemma M, Atanasiou T, Contino M. Minimally invasive cardiac surgery-coronary artery bypass graft [Electronic resource]. Multimed Man Cardio-Thoracic Surg. [URL] (date of access November 2, 2017).

22. Nambiar P., Mittal C. Minimally invasive coronary bypass using internal thoracic arteries via a left minithoracotomy «the Nambiar Technique». Innovations (Phila). 2013; 8(6): 420-426. doi: 10.1097/IMI.0000000000000035.

23. Zhbanov IV, Kiladze IZ, Uryuzhnikov VV, Shabalkin BV. Minimally invasive coronary artery bypass surgery. Russ. Jour. of Card. and Cardiovasc. Surg. Kard. i serd.-sosud. khir. 2019; 12(5): 377-385. (In Russ). doi: 10.17116/kardio201912051377.

For citation

Zhbanov I.V., Kiladze I.Z., Uryuzhnikov V.V., Martirosyan A.K., Shabalkin B.V. Immediate results of multiple minimally invasive coronary artery bypass grafting. Bulletin of Pirogov National Medical & Surgical Center. 2022;17(3):23-27. (In Russ.) https://doi.org/10.25881/20728255_2022_17_3_23