DOI: 10.25881/20728255_2022_17_1_143

Authors

Morgoshiia T.Sh.1, Syroezhin N.A.2

1 Surgical Department, St. Petersburg Clinical Hospital of the Russian Academy of Sciences, St. Petersburg

2 Research Clinical Institute of Pediatrics named after Academician Yu.E. Veltischev of the Russian National Research Medical University named after N.I. Pirogov, Moscow

Abstract

The main dates of the life and work of outstanding Soviet scientists S.S. Bryukhonenko and N.N. Terebinsky are presented. Their scientific cooperation is described. It is noted that the Autojector device, created by S.S. Bryukhonenko (1924), served as a prototype for all subsequent artificial blood circulation devices, both domestic and foreign, designed for interventions on the “open” heart. It is shown that an improved «Autojector» was used in intracardiac operations (performed by S.I. Chechulin), which were performed by Professor N.N. Terebinsky since 1929 (in the first operations together with S.S. Bryukhonenko) in the laboratory of the Research Chemical and Pharmaceutical Institute (NIHFI) led by Sergey Sergeevich (1926–1935). Artificial blood circulation during surgical operations on the heart, which allows to eliminate complex defects in the «open» heart under the control of vision, initiated by the experiments of S.S. Bryukhonenko and N.N. Terebinsky (1929), expanded the possibilities of cardiovascular surgery. Experiments with the «isolated head» of a dog conducted by S.S. Bryukhonenko and S.I. Chechulin were of great applied importance for cardiac surgery and transplantology. It is noted that the unique laboratory research on IC and the creation of the first device for the implementation of artificial blood circulation of the whole organism not only perpetuated the name of the talented and brilliant inventor Sergei Sergeevich, but also were important priorities of the USSR in world medical science. It is shown that domestic scientists S.S. Bryukhonenko and N.N. Terebinsky scientifically proved the possibility of: 1–artificial perfusion of the whole dog’s body, in particular the brain, oxygenated blood; 2-performing intracardiac operations under the control of vision with the use of artificial blood circulation. It is noted that N.N. Terebinsky’s experiments laid the foundation for further study of clinical cardiac surgery under the control of vision with the use of artificial blood circulation.

Keywords: artificial blood circulation, historical aspects, S.S. Bryukhonenko, N.N. Terebinsky, biography, autojector, «isolated head» of a dog, heart surgery, clinical death, revival of the body.

References

1. Mirsky MB. Surgery from antiquity to the present. Essays on history. M.: Nauka, 2000. 798 p. (In Russ).

2. Lapchinsky AG. S.S. Bryukhonenko — the founder of artificial blood circulation (A brief biographical sketch). M.: Science, 1964: 6-12. (In Russ).

3. Bogopolsky PM, Glyantsev SP, Loginov DT. Sergey Sergeevich Bryukhonenko — the creator of the method of artificial blood circulation (to the 125th anniversary of his birth). Cardiology and cardiovascular surgery. 2016; 6: 74-82. (In Russ).

4. Ivanyushkin AYa, Reznik ON, Popova OV. S.S. Bryukhonenko — the founder of artificial blood circulation technology (philosophical, methodological and socio-cultural context). Bulletin of Transplantology and artificial Organs. 2019; 21(4): 147-154. (In Russ).

5. Glyantsev SP. The phenomenon of genius: On the question of the origin and development of the idea of artificial blood circulation. Philosophical school. 2019; 9: 78-86. (In Russ).

6. Sirotkina MG, Gutkin VS. S.S. Bryukhonenko. M., 1972. 96 p. (In Russ).

7. Bryukhonenko SS, Chechulin SI. Experiments on isolating the dog’s head. In: Study of new methods of artificial blood circulation and blood transfusion. O.A. Steppun, editor. M., 1928: 7-12. (In Russ).

8. Bryukhonenko SS, Chechulin SI. Experiments on isolating the dog’s head. In: Bryukhonenko S.S. Artificial blood circulation. M.: Nauka, 1964: 15-54. (In Russ).

9. Bryukhonenko SS. Artificial blood circulation. Collection of works on artificial blood circulation. M.: Nauka, 1964. 284 p. (In Russ).

10. Bogopolsky PM. Zemsky surgeons and their role in the development of domestic medicine. History of medicine. 2015; 2(2): 217-226. (In Russ).

11. Bryukhonenko SS. Application of the method of artificial blood circulation to revitalize the body. Proceedings of the Research Institute of Experimental physiology and therapy. 1937; 1: 6-11. (In Russ).

12. Levit VS. Brief essays on the history of Soviet surgery. M.: Medgiz, 1960. 200 p. (In Russ).

13. Zhanetova MM. 140 years since the birth of Professor Nikolai Naumovich Terebinsky. Bulletin of Operative Surgery and Topographic Anatomy. 2020; 1(1): 14-19. (In Russ).

14. Morgoshiia TSh, Sergeeva GP. The development of domestic surgery of the heart and large vessels in the first half of the XX century. Angiology and vascular surgery. 2020; 26(4): 184-191. (In Russ).

15. Meshalkin EN. To the heights of art. Novosibirsk: Research Institute of Pathology of Blood circulation. 1997. 270 p. (In Russ).

16. Petrov IR. Oxygen starvation of the brain. L., 1949. 211 p. (In Russ).

17. Bogopolsky PM, Glyantsev SP. Nikolay Naumovich Terebinsky and his contribution to heart surgery (to the 75th anniversary of the publication of the monograph “Materials for the study of open access to atrioventricular heart valves”). Clinical and experimental surgery. Journal named after B.V. Petrovsky. 2015; 3: 5-17. (In Russ).

18. Mayat VS. Nikolay Naumovich Terebinsky (To the 95th anniversary of his birth). Surgery. The magazine named after N. I. Pirogov. 1975; 2: 147-148. (In Russ).

19. Terebinsky NN. Materials on the study of open access to atrioventricular heart valves. Experimental research. Moscow: Medgiz, 1940. 88 p. (In Russ).

20. Burakovsky VI, Gubler EV. Switching off the heart from the blood circulation under general cooling in an experiment. Proceedings of the XXVI Congress of Surgeons. Moscow, 1956. 177 p. (In Russ).

21. Burakovsky VI, Muravyev MV, et al. Surgery on a “dry” heart under hypothermia in the surgery of congenital heart defects. Thoracic surgery. 1961; 3: 15-19. (In Russ).

22. Proceedings of the XXV All-Union Congress of Surgeons. Moscow, October 1-8, 1946, Moscow: Medgiz, 1948. 588 p. (In Russ).

23. Terebinsky N.N. On experimental reproduction of heart valve defects, Dokl. USSR Academy of Sciences. 1930. (In Russ).

24. Terebinsky NN. Experimental stenosis of atrioventricular heart valves and their prompt elimination. Surgery. 1938; 12: 36-43. (In Russ).

For citation

Morgoshiia T.Sh., Syroezhin N.A. At the origins of the formation of the method of artificial blood circulation in the USSR. In memory of prominent scientists and innovators S.S. Bryukhonenko (1890-1960) and N.N. Terebinsky (1880–1959). Bulletin of Pirogov National Medical & Surgical Center. 2022;17(1):143-150. (In Russ.) https://doi.org/10.25881/20728255_2022_17_1_143