DOI: 10.25881/20728255_2021_16_2_142

Authors

Shevchenko Yu.L., Matveev S.A., Gudymovich V.G.

St. George thoracic and cardiovascular surgery clinic Pirogov National Medical and Surgical Center, Moscow

Abstract

In this article, we describe our pioneering experience of implantation of human embryonic cardiomyocytes to a patient with severe ischemic heart lesions. In 1998, we injected suspension of human embryonic cardiomyocytes into the myocardium of a 58-year-old male patient during coronary artery bypass surgery. Long follow-up (23 years) shows that the patient, who is currently 81 years old, feels good and has a good quality of life. He has no signs of circulatory insufficiency. No complications associated with cell implantation have ever been reported during this period.

Keywords: ischemic heart disease, cell replacement therapy, implantation of embryonic cardiomyocytes.

References

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For citation

Shevchenko Yu.L., Matveev S.A., Gudymovich V.G. Implantation of embryonic cardiomyocytes into the severely damaged myocardium (after 2 infarctions): 23-year follow-up. Bulletin of Pirogov National Medical & Surgical Center. 2021;16(2):142-145. (In Russ.) https://doi.org/10.25881/20728255_2021_16_2_142