DOI: 10.25881/BPNMSC.2020.20.88.016

Authors

Salukhov V.V.1, Gulayev N.I.2, Chepel A.I.1, Zemlyanoy A.B.3, Dorokhina E.V.1

1 Military Medical Academy. S.M. Kirov of the Ministry of Defense of Russia, St. Petersburg

2 3 Central Military Clinical Hospital named after A.A. Vishnevsky Ministry of Defense of Russia, Krasnogorsk

3 Pirogov National Medical and Surgical Center, Moscow

Abstract

Antiplatelet therapy in patients with coronary artery disease seems to be a complex clinical and pharmacological task due to the different sensitivity of patients to treatment and the complexity of control of therapy.

The review presents literature data on platelet resistance to antiplatelet therapy and its complications. The options for modifying antiplatelet therapy, ways of overcoming resistance and increasing its effectiveness are considered.

Keywords: IHD, antiplatelet therapy cardiovascular complications, primary prevention, acetylsalicylic acid.

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For citation

Salukhov V.V., Gulayev N.I., Chepel A.I., Zemlyanoy A.B., Dorokhina E.V. Preventive antiplatelet therapy of ischemic heart disease complications in conditions of variability of platelet response. Bulletin of Pirogov National Medical & Surgical Center. 2020;4(15):82-90. (In Russ.) https://doi.org/10.25881/BPNMSC.2020.20.88.016