DOI: 10.25881/BPNMSC.2018.73.55.022


Shevchenko Yu.L., Borshchev G.G.

National Medical and Surgical Center named after N.I. Pirogov, Moscow


The aim of the literature review was to analyze the effect of various endogenous growth factors on the stimulation of angiogenesis. The problems of regulation of neovasculogenesis processes in the body are considered. Similarly, the following growth factors are considered: vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), transforming growth factor (TGFp), hepatocyte growth factor (HGF), urokinase. The topic of the role of vitamins in neoangiogenesis is touched upon. In conclusion, studies are considered that address the use of angiogenesis stimulation factors in clinical practice -therapeutic angiogenesis.

Keywords: angiogenesis, vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), transforming growth factor (TGFp), hepatocyte growth factor (HGF), urokinase, therapeutic angiogenesis.


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For citation

Shevchenko Yu.L., Borshchev G.G. Stimulation of angiogenesis with endogenic growth factors. Bulletin of Pirogov National Medical & Surgical Center. 2018;13(3):96-102. (In Russ.)