DOI: 10.25881/BPNMSC.2019.63.22.023

Authors

Solovev I.A., Litvinov O.A., Navmatulja A.Yu., Zhitihin E.V.

The S.M. Kirov Military Medical Academy, St. Petersburg

Abstract

Summary data of contemporary literature focuses on a patients with rectal carcinoma that have problem of colorectal anastomotic failure. The article presents an analysis of preoperative, intraoperative, postoperative anastomotic leakage risk factors and methods of anastomotic leakage prevention.

Keywords: rectal cancer, anastomotic leakage, risk factors, complications, prevention.

References

1. Alekseev, M.V., SHelygin, YU.A., Rybakov, E.G. Metody profilaktiki nesostoyatel’nosti kolorektal’nogo anastomoza (obzor literatury) // Koloproktologiya. – 2015. – №. 4. – Р. 46–56.

2. Bordakov, V.N., Dronin, M.V., Bordakov, P.V. EHksperimental’noe izuchenie ehffektivnosti lekarstvennogo sredstva «Fibrinostat M» // Voennaya medicina. – 2013. – №. 4. – Р. 29–32.

3. Vorob’ev, G.I., Eropkin, P.V., Rybakov, E.G., Peresada I.V., CHernyshev S.V. Metody i rezul’taty vosstanovitel’nyh operacij u pacientov s preventivnymi kishechnymi stomami // Koloproktologiya. – 2007. – № 3. – Р. 22–27.

4. Vorob’ev, G.I., Sevost’yanov, S.I., CHernyshov, S.V. Vybor optimal’nogo vida preventivnoj kishechnoj stomy // Novosti koloproktologii. – 2007. – №. 2. – Р. 69–74.

5. Em, A.E. Preventivnye kishechnye stomy pri sfinkterosohranyayushchih operaciyah po povodu raka pryamoj kishki : dis. kand. med. nauk: 14.00.27 / Em Aleksandr Engirovich. – SPb., 2008. – 119 р.

6. Ermakov, D.F. Faktory riska nesostoyatel’nosti apparatnogo anastomoza posle perednej rezekcii pryamoj kishki : avtoref. dis. kand. med. nauk : 14.01.17 / Ermakov Dmitrij Fedotovich. – M., 2012. – 24 р.

7. Ibragimov, R.M. Opyt primeneniya bioehksplanta na osnove modificirovannoj gialuronovoj kisloty dlya profilaktiki nesostoyatel’nosti anastomozov polyh organov (ehksperimental’noe issledovanie) // Byulleten’ Sibirskogo otdeleniya Rossijskoj akademii medicinskih nauk. – 2009. – T. 29, № 6. – Р. 19–23.

8. Kalivo, EH.A., Manihas, G.M., Hanevich, M.D., Fridman, M.H., Hrykov, G.N. Metod «skrytoj kolostomii» pri nizkih perednih rezekciyah primoj kishki // Vestnik hirurgii im. I.I. Grekova. – 2016. – T. 6, № 175. – Р. 52–55.

9. Mel’nikov, P.V., YAkovlev, E.V., Savenkov, S.V., Eres’ko, D.V. Psevdomembranoznyj kolit, oslozhnennyj toksicheskim megakolonom, posle zakrytiya preventivnoj stomy // Onkologicheskaya koloproktologiya. – 2016. – T. 6, № 2. – Р. 47–50.

10. Nesterov, M.I., Ramazanov, M.R., Gaziev, R.M., Magomedov, A.M., Aliev, EH.A. Prakticheskie rezul’taty primenenie apparata dlya issledovaniya nasyshcheniya kislorodom gemoglobina arterial’noj krovi i intramural’nogo davleniya pri formirovanii mezhkishechnyh anastomozov // Sovremennye problemy nauki i obrazovaniya. – 2014. – № 3. – Р. 542–545.

11. Polovinkin, V.V., Prohanov, V.A., Zavrazhnov, A.A., Volkov, A.V., Halafyan, A.A. Faktory riska razvitiya nesostoyatel’nosti kolorektal’nogo anastomoza posle operacij po povodu raka pryamoj kishki // Kubanskij nauchnyj medicinskij vestnik. – 2013. – № 7. – Р. 106–112.

12. Popov, D.E. Faktory riska nesostoyatel’nosti kolorektal’nyh anastomozov u bol’nyh rakom pryamoj kishki // Koloproktologiya. – 2014. – № 2 (48). – Р. 48–56.

13. Rychagov, G.P., Barsukov, K.N. Mesto relaparotomii v hirurgii tolstoj kishki // Hirurgiya Vostochnaya Evropa. – 2012. – № 1. – Р. 110-111.

14. CHerdancev, D.V., Pozdnyakov, A.A., SHpak, V.V., Ryabkov, YU.V., Popov, A.E. Nesostoyatel’nost’ kolorektal’nogo anastomoza. Sovremennoe sostoyanie problemy (obzor literatury) // Koloproktologiya. – 2015. – № 4 (54). – Р. 57-64.

15. SHurkalin, B.K., Gorskij, V.A., Volenko, A.V., Faller, A.P., Leonenko, I.V., Andreev, S.S., Il’in, V.A. Vozmozhnosti, rezul’taty i perspektivy ukrepleniya kishechnyh shvov fibrin-kollagenovoj substanciej “TahoKomb” // Hirurgiya. – 2004. – № 2. – Р. 53–55.

16. Amin, A.I., Ramalingam, Т., Sexton, R., Heald, R.J., Leppington-Clarke, A., Moran, B.J. Comparison of transanal stent with defunctioning stoma in low anterior resection for rectal cancer // Br J Surg. – 2003. – Vol. 90 (5). – P. 581–582.

17. Baek, S.J., Kim, J., Kwak, J., Kim, S.H. Can transanal reinforcing sutures after double stapling in lower anterior resection reduce the need for a temporary diverting ostomy? // World J Gastroenterol. – 2013. – Vol. 19 (32). – P. 5309–5313.

18. Bhangu, A., Nepogodieу, D., Futaba, К. West Midlands Research Collaborative. Systematic review and meta-analysis of the incidence of incisional hernia at the site of stoma closure // World J Surg. – 2012. – Vol. 36 (5). – Р. 973-983.

19. Brennan, D.J., Moynagh, М., Brannigan, А.Е., Gleeson F., Rowland M., O, Connell P.R. Routine mobilization of the splenic flexure is not necessary during anterior resection for rectal cancer // Dis Colon Rectum. – 2007. – Vol. 50 (3). – Р. 302–307.

20. Bulow, S., Bulut, О., Christensen, I.J., Harling, H., Rectal Stent Study Group. Transanal stent in anterior resection does not prevent anastomotic leakage // Colorectal Dis. – 2006. – Vol. 8 (6). – P. 494–496.

21. Carli, F., Mayo, N., Klubien, К., Schricker, T., Trudel, J., Belliveau, P. Epiduralanalgesia enhances functional exercise capacity and health-related quality of life after colonic surgery: results of a randomized trial // Anesthesiology. – 2002. – Vol. 97 (3). – Р. 540–549.

22. Chow, А., Tilney, H.S., Paraskeva, Р., Jeyarajah, S., Zacharakis, E., Purkayastha, S. Тhe morbidity surrounding reversal of defunctioning ileostomies: a systematic review of 48 studies including 6,107 cases // Int J Colorectal Dis. – 2009. – Vol. 24 (6). – Р. 711–723.

23. Davies, А.Н., Bartolo, D.C., Richards, A.E., Johnson, C.D., Mc C Mortensen, N.J. Introoperative air testing: an audit on rectal anastomosis // Ann R Coll Surg Engl. – 1988. – Vol. 70 (6). – Р. 345–347.

24. De Luca, R., Caliandro, С., Ruggieri, Е. Rectal cancer proctectomy without covering stoma. The «G. Paolo II» Cancer Research Centre experience // EJSO. – 2014. – Vol. 40 (11). – P. 115–116.

25. Den Dulk, М., Marijnen, С.А, Collette, L., Putter, Н., Påhlman, L., Folkesson, J., Bosset, J.F., Rödel, С., Bujko, К., van de Velde, C.J. Multicentre analysis of oncological and survival outcomes 223 following anastomotic leakage after rectal cancer surgery // Br J Surg. – 2009. – Vol. 96 (9). – Р. 1066–1075.

26. Farke, S., Bouchard, R. Mobilization of the splenic flexure: a standard in laparoscopic left colon and rectum resections // Surgery J. – 2010. – Vol. 5 (3). – Р. 31–35.

27. Fa-Si-Oen, Р., Roumen, R., Buitenweg, J., van de Velde, C., van Geldere, D., Putter, H., Verwaest, C., Verhoef, L., de Waard, J.W., Swank, D., D,Hoore, A., Croiset van Uchelen F. Mechanical bowel preparation or not? Outcome of a multicenter, randomized trial in elective open colon surgery // Dis Colon Rectum. – 2005. – Vol. 48 (8). – Р. 1509–1516.

28. Gooszen, A.W., Geelkerken, R.H., Hermans, J., Lagaay, M.B., Gooszen, H.C. Тemporary decompression after colorectal surgery: randomized comparison of loop ileostomy and loop colostomy // Br J Surg. – 1998. – Vol. 85 (1). – Р. 76–79.

29. Guenaga, K.F., Matos, D., Castro, А.А., Atallah, A.N., Wille-Jorgensen, P. Mechanical bowel preparation for elective colorectal surgery // Cochrane Database Syst Rev. – 2005. – Vol. 25 (1): CD001544.

30. Hartley, M.N., Sagar, Р.М. The surgeon ‘gut feeling’ as a predictor of post-operative outcome // Ann R Coll Surg Engl. – 1994. – Vol. 76 (6). – Р. 277–278.

31. Hidaka, Е., Ishida, F., Mukai, S., Nakahara, K., Takayanagi, D., Maeda, C., Takehana, Y., Tanaka, J., Kudo, S.E. Еfficacy of transanal tube for prevention of anastomotic leakage following laparoscopic low anterior resection for rectal cancers: a retrospective cohort study in a single institution // Surg Endosc. – 2015. – Vol. 29 (4). – P. 863–867.

32. Hirano, Y., Omura, К., Tatsuzawa, Y., Shimizu, J., Kawaura, Y., Watanabe, G. Tissue oxygen saturation during colorectal surgery measured by near-infrared spectroscopy: pilot study to predict anastomotic complications // World J Surg. – 2006. – Vol. 30 (3). – P. 457–461.

33. Hua, Н., Xu J., Chen, W., Zhou, X., Wang, J., Sheng, Q., Lin, J. Defunctioning cannula ileostomy after lower anterior resection of rectal cancer // Dis Colon Rectum. – 2014. – Vol. 57 (11). – P. 1267–1274.

34. Huh, J.W. Park, Y.A., Sohn, S.K. А diverting stoma is not necessary when performing a handsewn coloanal anastomosis for lower rectal cancer // Dis Colon Rectum. – 2007. – Vol. 50 (7). – Р. 1040–1046.

35. Jung, В., Pahlman, L. Мulticentre randomized clinical trial of mechanical bowel preparation in elective colonic resection // Br J Surg. – 2007. – № 94. – Р. 689–695.

36. Kim, M.K., Won, D.Y., Lee, J.K., Kang, W.K., Kim, J.G., Oh, S.T. Сomparative study between transanal tube and loop ileostomy in low anterior resection for mid rectal cancer: a retrospective single center trial. // Ann Surg Treat Res. – 2015. – Vol. 88 (50). – P. 260–268.

37. Konishi, Т., Watanabe, Т., Kishimoto, J., Nagawa, H. Risk factors for anastomotic leakage after surgery for colorectal cancer: results of prospective surveillance // J Am Col Surg. – 2006. – Vol. 202 (3). – Р. 439–444.

38. Kudszus, S., Roesel, С., Schachtrupp, А., Hoer, J.J. Intraoperative laser fluorescence angiography in colorectal surgery: a noninvasive analysis to reduce the rate of anastomotic leakage // Langenbecks Arch Surg. – 2010. – Vol. 395 (8). – Р. 1025–1030.

39. Miccini, М., Bonapasta, S.A., Gregori, М., Barillari, H., Tocchi, A. Ghost ileostomy: real and potential advantages // Am J Surg. – 2010. – № 200. – Р. 55–57.

40. Moran, B.J. Predicting the risk and diminishing the consequences of anastomotic leakage after anterior resection for rectal cancer // Acta Chir Iugosl. – 2010. – Vol. 57 (3). – Р. 47–50.

41. Mori, L., Vita, М., Razzetta, F., Meinero, P., D, Ambrosio, G. Ghost ileostomy in anterior resection for rectal carcinoma: is it worthwhile? // Dis Colon Rectum. – 2013. – Vol. 56 (1). – Р. 29–34.

42. Peeters, К.С., Tollenaar, R.A., Marijnen, С.А., Klein Kranenbarg, E., Steup, W.H., Wiggers,T., Rutten, H.J., van de Velde, C.J., Dutch Colorectal Cancer Group. Risk factors for anastomotic failure after total mesorectal excision of rectal cancer // Br J Surg. – 2005. – Vol. 92 (2). – Р. 211-216.

43. Portillo, G., Franklin, М.Е. Clinical results using bioabsorbable staple-line reinforcement for circular stapler in colorectal surgery: a multicenter study // J Laparoendosc Adv Surg Tech A. – 2010. – Vol. 20 (4). – Р. 323–327.

44. Rondelli, F., Reboldi, Р., Rulli, А., Barberini, F., Guerrisi, A., Izzo, L., Bolognese, A., Covarelli, P., Boselli, C., Becattini, C., Noya, G. Loop ileostomy versus loop colostomy for fecal diversion after colorectal or coloanal anastomosis: a meta-analysis // Int J Colorect Dis. – 2009. – Vol. 24 (5). – Р. 479–488.

45. Rubio-Perez, I., Leon, М., Pastor, D., Diaz Dominguez, J., Cantero, R. Increased postoperative complications after protective ileostomy closure delay: An institutional study // World J Gastrointest Surg. – 2014. – Vol. 6 (9). – Р. 169–174.

46. Rullier, Е., Le Toux, N., Laurent, С., Garrelon, S.L., Parneix, M., Saric, J. Loop ileostomy versus loop colostomy for defunctioning low anastomoses during rectal cancer surgery // World J Surg. – 2001. – Vol. 25 (3). – Р. 274–277.

47. Saha, А.К., Tapping, C.R., Foley, G.T., Baker, R.P., Sagar, P.M., Burke, D.A., Sue-Ling, H.M., Finan, P.J. Мorbidity and mortality after closure of loop ileostomy // Colorectal Dis. – 2009. – № 11. – Р. 866–871.

48. Senagore, А., Lanе, F.R., Lee, Е., Wexner, S., Dujovny, N., Sklow, B., Rider, P., Bonello, J., Bioabsorbable Staple Line Reinforcement in Restorative Proctectomy and Anterior Resection: A Randomized Study // Dis Colon Rectum. – 2014. – Vol. 57 (3). – P. 324–330.

49. Thalheimer, А., Bueter, М., Kortuem, М., Thiede, A., Meyer, D. Мorbidity of temporary loop ileostomy in patients with colorectal cancer // Dis Colon Rectum. – 2006. – Vol. 49 (7). – Р. 1011–1017.

50. Tsujinaka, S., Kawamura, Y.J., Konishi, F., Maeda, T., Mizokami, K. Pelvic drainage for anterior resection revisited: use of drains in anastomotic leaks // ANZ J Surg. – 2008. – Vol. 78 (6). – Р. 461–465.

51. Vignali, A., Gianotti, L., Braga, M., Radaelli, G., Malvezzi, L., Di Cario, V. Altered microperfusion at the rectal stamp is predictive fo rectal anastomotic leak // Dis Colon Rectum. – 2000. – Vol. 43 (1). – P. 76–82.

52. Wilson, M.Z., Hollenbeak, C.S., Stewart, D.B. Impact of Clostridium difficile colitis following closure of a diverting loop ileostomy: results of a matched cohort study // Colorecal Dis. – 2013. – Vol. 15 (8). – Р. 974–981.

53. Ye, F., Chen, D., Wang, D., Lin, J., Zheng, S. Use of Valtractm-secured intracolonic bypass in laparoscopic rectal cancer resection // Medicine (Baltimore). – 2014. – Vol. 93 (29). – Р. 224.

54. Ye, F., Wang, D., Xu, Х., Liu, F., Lin, J. Use of Intracolonic Bypass secured by a biodegradable anastomotic ring to protect the low rectal anastomosis // Dis Colon Rectum. – 2008. – Vol. 51 (1). – P. 109–115.

55. Zhao, W.T., Hu, F.L., Li, Y.Y., Li, H.J., Luo, W.M., Sun, F. Use of a transanal drainage tube for prevention of anastomotic leakage and bleeding after anterior resection for rectal cancer // World J Surg. – 2013. – Vol. 37 (1). – P. 227–232.

For citation

Solovev I.A., Litvinov O.A., Navmatulja A.Yu., Zhitihin E.V. Risc factors of colorectal anastomotic failure and methods of anastomotic leakage prevention. Bulletin of Pirogov National Medical & Surgical Center. 2019;14(1):125-133. (In Russ.) https://doi.org/10.25881/BPNMSC.2019.63.22.023