DOI: 10.25881/BPNMSC.2020.29.19.029


Butareva D.V., Hanaliev B.V., Daminov V.D.

Pirogov National Medical and Surgical Center, Moscow


This article provides a review of the literature on the use of botulinum toxin type A in urological practice, the definition of indications, contraindications to this type of treatment and methods of administration of this drug. The most common conservative treatment for an overactive bladder is the administration of anticholinergic drugs, but sometimes the effect of M-holinoblockers is either insufficient or poorly tolerated due to a large number of adverse reactions. According to the literature, lower urinary tract dysfunction occurs in 17% of the population and can lead to chronic kidney disease and reduce the quality of life. One of the fundamentally new directions among the methods of treatment overactive bladder of various etiologies is the introduction of botulinum toxin type A into the muscle layer of the bladder wall, which has shown good results.

Keywords: urology, neurourology, botulinum toxin A, urinary incontinence, imperative urges, overactive bladder, urinary tract syndrome, painful bladder syndrome, interstitial cystitis, intravesical administration, detrusor, comprehensive urodynamic study.


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For citation

Butareva D.V., Hanaliev B.V., Daminov V.D. Use of botulinum toxin type A in urological practice. Bulletin of Pirogov National Medical & Surgical Center. 2020;15(3-2):166-171. (In Russ.)