DOI: 10.25881/BPNMSC.2020.80.13.022


Kachnov V.A.

FGBVOU VO «Military medical Academy n.a. S.M. Kirov» MO RF, Saint-Petersburg


In the structure of fatal outcomes from cardiovascular diseases, sudden cardiac death in young and middle-aged people compose 17.8%. A single comprehensive model for assessing the risk of sudden cardiac death has not yet been developed, and the diseases that lead to its development often occur latently and are not diagnosed during life. Screening for risk factors for sudden cardiac death and further stratification in the general population among young and middle-aged people requires a relatively simple and cheap model for estimating the likelihood of its occurrence. The article presents an algorithm for identifying risk factors and stratifying the risk of sudden cardiac death in young and middle-aged people, which includes questionnaires, electrocardiography, objective examination, medical examination and genetic testing.

Keywords: sudden cardiac death, risk factors, diagnostic algorithm, stratification of risk factors, young and middle-aged persons.


1. Malkov PV, Baranov EF, Bezborodova TS, et al. Rossiiskii statisticheskii ezhegodnik. 2019: Statisticheskii sbornik. Moscow: Rosstat; 2019. 708 p.

2. Boytsov SA, Linchak RM, Nedbaikin AM, et al. Epidemiology of sudden cardiac death: what do we know today? Klinicheskaya praktika. 2014;(4):13–18.

3. Shlyakhto EV, Arutyunov GP, Belenkov YuN, et al. Natsional'nye rekomendatsii po opredeleniyu riska i profilaktike vnezapnoi serdechnoi smerti. 2nd ed. Moscow: Medpraktika-M; 2018. 247 p.

4. Osman J, Tan SC, Lee PY, et al. Sudden Cardiac Death (SCD) — risk stratification and prediction with molecular biomarkers. J Biomed Sci. 2019;26(1):39. doi: 10.1186/s12929-019-0535-8.

5. Liew R. Sudden cardiac death risk stratification — an update. Eur Cardiol. 2015;10(2):118–122. doi: 10.15420/ecr.2015.10.2.118.

6. Chen H, Deng Y, Li S. Relation of body mass index categories with risk of sudden cardiac death. Int Heart J. 2019;60(3):624–630. doi: 10.1536/ihj.18-155.

7. Aune D, Schlesinger S, Norat T, Riboli E. Tobacco smoking and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies. Eur J Epidemiol. 2018;33(6):509–521. doi: 10.1007/s10654-017-0351-y.

8. Linchak RM, Nedbaikin AM, Sementsova EV, et al. The role of alcohol in the development of sudden cardiac death according to the Germin's register (register of sudden cardiac mortality in the working-age population of the Bryansk region). Rossiiskii kardiologicheskii zhurnal. 2017;22(6):108–112. doi: 10.15829/1560-4071-2017-6-108-112.

9. Rao P, Hutter AM, Baggish AL. The limits of cardiac performance: can too much exercise damage the heart? Am J Med. 2018;131(11):1279–1284. doi: 10.1016/j.amjmed.2018.05.037.

10. Kachnov VA, Tyrenko VV, Kolyubaeva SN, et al. Acquired prolonged QT interval syndrome: causes and prevention options to reduce sudden cardiac death. Russkii meditsinskii zhurnal. Meditsinskoe obozrenie. 2019;3(10–1):18–22.

11. Holkeri A, Eranti A, Anette M, et al. Predicting sudden cardiac death in a general population using an electrocardiographic risk score. Heart. 2020;106(6):427–433. doi: 10.1136/heartjnl-2019-315437.

12. Steinberg S, Varma N, Cygankiewicz I, et al. 2017 ISHNE-HRS Expert Consensus Statement on Ambulatory ECG and External Cardiac Monitoring/Telemetry. Heart Rhythm. 2017;14(7):e55–e96. doi: 10.1016/j.hrthm.2017.03.038.

For citation

Kachnov V.A. Stratification, risk factors and diagnostic algorithm of sudden cardiac death in the general population in young and middle-aged persons. Bulletin of Pirogov National Medical & Surgical Center. 2020;3-2(15):119-123. (In Russ.)