DOI: 10.25881/20728255_2021_16_3_18

Authors

Glazkova P.A.1, Babenko A.Yu.2, Kononova Yu.A.2, Glazkov A.A.1, Zagarov S.S.1, Kovaleva Yu.A.1, Lar’kov R.N.1, Britvin T.A.1, Mazur N.N.1, Kulikov D.A.1, 3, Rogatkin D.A.1

1 Moscow Regional Research and Clinical Institute («MONIKI»), Moscow

2 Almazov National Medical Research Centre, St. Petersburg

3 Moscow Region State University, Mytishchi

Abstract

Background: To date, the development of new scales that, based on routine laboratory and instrumental examinations, would allow an integral assessment of the severity of cardiovascular system damage in patients with diabetes mellitus is relevant. The development of such scales can help to objectively rank patients according to the severity of damage to the cardiovascular system in clinical and scientific research aimed at creating new instrumental methods for assessing hemodynamic disorders.

Aim: development of a scale for scoring the severity of damage to the cardiovascular system in patients with diabetes.

Materials and methods. To apply the developed scale, 18 diabetic patients were included in the study, divided into two contrast groups: group 1 — patients without vascular complications of diabetes mellitus (n = 9), group 2 — patients with diabetic foot syndrome of DM (n = 9). All subjects underwent laboratory and instrumental examinations to diagnose diabetes complications.

Results. The scale for scoring the severity of functional impairment of the cardiovascular system in patients with diabetes mellitus was developed. The scale is including 5 categories: lower extremity arterial disease; cardiac and cerebrovascular disease; diabetic nephropathy; diabetic retinopathy; and diabetic neuropathy. Approbation of the scale showed that median scores in group 1 were significantly higher than in group 2 (2.5 [2; 3] points vs. 10.5 [8; 12] points, p<0.001). This result is consistent with the clinical picture. Using this approach also allows patients to be ranked according to the severity of their cardiovascular involvement within groups. Patients in group 2 with a high score have a more severe vascular lesion than patients in the same group with a lower score.

Conclusion: a scale for the objective integral scoring of cardiovascular severity in diabetic patients has been developed. The scale can be used for scientific and clinical studies involving diabetic patients.

Keywords: diabetes mellitus, cardiovascular system, diabetes complications.

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For citation

Glazkova P.A., Babenko A.Yu., Kononova Yu.A., Glazkov A.A., Zagarov S.S., Kovaleva Yu.A., Lar’kov R.N., Britvin T.A., Mazur N.N., Kulikov D.A., Rogatkin D.A. Scale for scoring the severity of functional impairment of the cardiovascular system in patients with diabetes mellitus. Bulletin of Pirogov National Medical & Surgical Center. 2021;3(16):18-24. (In Russ.) https://doi.org/10.25881/20728255_2021_16_3_18