DOI: 10.25881/BPNMSC.2020.79.30.013

Authors

Gromov A.L.1, Gubin M.A.2, Ivanov S.V.1, Schenin A.V.1

1 Kursk State Medical University, Kursk

2 Voronezh State Medical University. N.N. Burdenko, Kursk

Abstract

57 patients with odontogenic sepsis were analyzed. Two subgroups were identified: main – 34 patients with odontogenic sepsis, developing in the presence of background diseases of the cardiovascular, respiratory, digestive and other systems; control – with odontogenic sepsis without background pathology.

Results. Odontogenic sepsis is generally characterized by tachycardia more than 100 in 1 min, high values of the systolic index (more than 3–3.5 l/min × m2), heart volume less than 70 ml the presence of background diseases in patients with odontogenic sepsis causes a statistically significant increase in the frequency of respiratory movements and the severity of anemia in comparison with a similar group without background pathology.

Conclusion. Odontogenic sepsis is characterized by rapid development and short duration of the disease (the average period of hospitalization is about 20 bed days), except for cases of contact odontogenic mediastinitis, characterized by long periods of hospitalization. Complications in odontogenic sepsis develop in 50–70% of cases, and in the group of patients with background pathology complications lead to death more often than in the same group without background diseases.

Keywords: infection, purulent process, maxillofacial area, sepsis, background pathology.

References

1. Andreev AV, Morozov MP. Vazopressin i ego analogi v terapii septicheskogo shoka. Zdravookhranenie Chuvashii. 2017;(4):52–62. (In Russ).

2. Gel’fand BR, Eremenko AA, Protsenko DN, et al. Infuzionnaya terapiya pri tyazhelom sepsise i septicheskom shoke. Vestnik intensivnoy terapii. 2006;(3):33–38. (In Russ).

3. Gubin MA, Vodolazskiy NYu, Gromov AG, Oganesyan AA. Vrachebnaya taktika kompleksnogo lecheniya gnoinykh khirurgicheskikh zabolevanii litsa i shei u patsientov s fonovoi poliorgannoi patologiei. In: Ctomatologiya slavyanskikh gosudarstv, sbornik trudov Kh Mezhdunarodnoi nauchno-prakticheskoi konferentsii, posvyashchennoi 25-letiyu ZAO «OEZ «VladMiVa». Belgorod: Belgorod; 2017. P. 136–143. (In Russ).

4. Gubin MA, Ivanov SV, Gromov AL, Vodolazskiy NYu. Kharakteristika fonovoi patologii u patsientov s vospalitel’nymi zabolevaniyami litsa i shei. Kurskii nauchno-prakticheskii vestnik chelovek i ego zdorov’e. 2017;(2):45–48. (In Russ). doi: 10.21626/vestnik/2017-2/08.

5. Gubin MA, Kharitonov YuM, El’kova NL. Analiz rezul’tatov diagnostiki i lecheniya sepsisa u stomatologicheskikh bol’nykh. System analysis and management in biomedical systems. 2004;3(1):57–60. (In Russ).

6. Gubin MA, Kharitonov YuM, El’kova NL, Kikov RN. Itogi izucheniya sepsisa u stomatologicheskikh bol’nykh. Prikladnye informatsionnye aspekty meditsiny. 2003;6(2):55–61. (In Russ).

7. Zavada NV, Gain YuM, Alekseev SA. Khirurgicheskii sepsis. Minsk: Novoe znanie; 2003. P. 237. (In Russ).

8. Kursov SV, Mikhnevich KG. Aspekty gemodinamicheskoi podderzhki pri septicheskom shoke. Emergency medicine. 2012;5(44):18–23. (In Russ).

9. Muzdubaeva BT. Monitoring gemodinamiki pri sepsis. Vestnik kazakhskogo natsional’nogo meditsinskogo universiteta. 2016;(2):14–16. (In Russ).

10. Muzdubaeva BT. Narusheniya miokardial’noi funktsii pri sepsis. Annaly khirurgii. 2016;21(5):293–299. (In Russ).

11. Oganesyan AA, Kulikovskii VF. Algoritmy diagnostiki anaerobnoi infektsii u bol’nykh s gnoinymi khirurgicheskimi zabolevaniyami litsa i shei. Belgorod State University scientific bulletin. Medicine, pharmacy. 2011;105(10):108–111. (In Russ).

12. Rudnov VA. Infuzionno-transfuzionnaya terapiya kak komponent intensivnoi terapii sepsis. Khirurgiya. Prilozhenie k zhurnalu Consilium Medicum. 2005;(1):54–57. (In Russ).

13. Sachko AA. Otsenka sistemy krovoobrashcheniya u bol’nykh s khirurgicheskimi infektsiyami, oslozhnennymi sepsisom. Vestnik khirurgii Kazakhstana. 2012;2(30):100–101. (In Russ).

14. Kharitonov YuM, Lenev VN. Kliniko-laboratornaya diagnostika ostrykh vospalitel’nykh zabolevanii chelyustno-litsevoi oblasti i shei, vyzvannykh anaerobnoi infektsiei. Vestnik eksperimental’noi i klinicheskoi khirurgii. 2009;2(1):60–63. (In Russ).

For citation

Gromov A.L., Gubin M.A., Ivanov S.V., Schenin A.V. Characteristic of hemodynamics and metabolism in patients with acute odontogenic sepsis with background multi-organ pathology. Result of treatment. Bulletin of Pirogov National Medical & Surgical Center. 2019;14(4):62-66. (In Russ.) https://doi.org/10.25881/BPNMSC.2020.79.30.013